SCHEMBL29669698

SCHEMBL29669698

N#Cc1ccc2oc3ccc(Br)cc3c2c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 1/20 0.46
PIM1 P11309 2/20 0.42
CYP2A6 P11509 1/20 0.42
NOS3 P29474 1/20 0.41
NOS1 P29475 1/20 0.41
NOS2 P35228 1/20 0.41
MAOA P21397 1/20 0.40
MAOB P27338 1/20 0.40
CA12 O43570 3/20 0.40
CA9 Q16790 3/20 0.40
GABRP O00591 4/20 0.38
GABRD O14764 4/20 0.38
GABRA1 P14867 4/20 0.38
GABRB1 P18505 4/20 0.38
GABRG2 P18507 4/20 0.38
GABRB3 P28472 4/20 0.38
GABRA5 P31644 4/20 0.38
GABRA3 P34903 4/20 0.38
GABRA2 P47869 4/20 0.38
GABRB2 P47870 4/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15240406 1.00 KCNH2 (0.46) KCNH2PIM1CYP2A6NOS3NOS1
SCHEMBL30482504 0.91 KCNH2 (0.40) KCNH2PIM1CYP2A6NOS3NOS1
SCHEMBL24403794 0.90 PIM1 (0.45) KCNH2PIM1NOS3NOS1NOS2
SCHEMBL548410 0.88 CYP2A6 (0.50) PIM1CYP2A6NOS3NOS1NOS2
SCHEMBL17706368 0.82 PGR (0.45) CYP2A6MAOAMAOBGABRPGABRD
SCHEMBL258689 0.82 PIM1 (0.55) KCNH2PIM1CYP2A6CA12CA9
SCHEMBL15763533 0.81 MAOB (0.40) KCNH2CYP2A6NOS3NOS1NOS2
SCHEMBL20282452 0.81 PGR (0.47) PIM1CYP2A6NOS3NOS1NOS2
SCHEMBL11554110 0.81 CYP2A6 (0.44) PIM1CYP2A6NOS3NOS1NOS2
SCHEMBL20282639 0.81 PGR (0.47) PIM1CYP2A6NOS3NOS1NOS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110869366-B Heterocyclic compound and organic light-emitting device comprising same 株式会社LG化学 2023-07-04 CN disclosed
CN-106432211-B Condensed ring compound and organic light emitting device including the same 三星电子株式会社 2022-06-03 CN disclosed