Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | CDC7 | O00311 | 2/20 | 0.63 |
| ▸ | DBF4 | Q9UBU7 | 2/20 | 0.63 |
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3593014 | 1.00 | ALDH1A1 (0.68) | ALDH1A1LMNACDC7DBF4NPC1 | |
| SCHEMBL2161303 | 0.84 | ALDH1A1 (0.73) | ALDH1A1LMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL23794771 | 0.84 | CDC7 (0.60) | ALDH1A1LMNACDC7DBF4NPC1 | |
| SCHEMBL2225549 | 0.83 | CDC7 (0.79) | ALDH1A1LMNACDC7DBF4NPC1 | |
| SCHEMBL18093555 | 0.82 | CDC7 (0.61) | ALDH1A1LMNACDC7DBF4NPC1 | |
| SCHEMBL29728129 | 0.82 | CDC7 (0.61) | ALDH1A1LMNACDC7DBF4NPC1 | |
| SCHEMBL23794647 | 0.82 | CDC7 (0.61) | ALDH1A1LMNACDC7DBF4NPC1 | |
| SCHEMBL13185669 | 0.82 | KDM4E (0.61) | ALDH1A1LMNACDC7DBF4NPC1 | |
| SCHEMBL1313344 | 0.81 | ALDH1A1 (1.00) | ALDH1A1LMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL23146170 | 0.81 | CDC7 (0.63) | ALDH1A1LMNACDC7DBF4NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4034106-A1 | THIAZOLE CARBOXAMIDE COMPOUNDS AND USE THEREOF FOR THE TREATMENT OF MYCOBACTERIAL INFECTIONS | The Global Alliance for TB Drug Development, Inc. (US) | 2022-08-03 | — | — | EP | disclosed |
| CN-114746089-A | Thiazolecarboxamide compounds and their use for the treatment of mycobacterial infections | 结核病药物开发全球联盟公司 | 2022-07-12 | — | — | CN | disclosed |