Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5C | P41229 | 9/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 1.00 |
| ▸ | KDM4C | Q9H3R0 | 7/20 | 1.00 |
| ▸ | KDM2A | Q9Y2K7 | 6/20 | 1.00 |
| ▸ | KDM3A | Q9Y4C1 | 6/20 | 1.00 |
| ▸ | KDM6B | O15054 | 5/20 | 1.00 |
| ▸ | JMJD6 | Q6NYC1 | 2/20 | 0.66 |
| ▸ | KDM4A | O75164 | 6/20 | 0.60 |
| ▸ | KDM5B | Q9UGL1 | 7/20 | 0.59 |
| ▸ | P4HA1 | P13674 | 1/20 | 0.58 |
| ▸ | KDM4B | O94953 | 3/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | KDM5A | P29375 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | TET3 | O43151 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2868531 | 1.00 | KDM5C (1.00) | KDM5CKDM4EKDM4CKDM2AKDM3A | |
| SCHEMBL10052344 | 0.94 | KDM5C (0.88) | KDM5CKDM4EKDM4CKDM2AKDM3A | |
| SCHEMBL70279 | 0.93 | KDM4E (0.86) | KDM5CKDM4EKDM4CKDM2AKDM3A | |
| SCHEMBL29894587 | 0.93 | KDM4E (0.86) | KDM5CKDM4EKDM4CKDM2AKDM3A | |
| SCHEMBL6514670 | 0.91 | KDM4E (0.83) | KDM5CKDM4EKDM4CKDM2AKDM3A | |
| Hydrochloric Acid SCHEMBL6504834 | 0.91 | KDM4E (0.83) | KDM5CKDM4EKDM4CKDM2AKDM3A | |
| SCHEMBL30774379 | 0.86 | KDM4E (0.76) | KDM5CKDM4EKDM4CKDM2AKDM3A | |
| SCHEMBL714108 | 0.86 | KDM4E (0.76) | KDM5CKDM4EKDM4CKDM2AKDM3A | |
| SCHEMBL19229659 | 0.86 | KDM4E (0.76) | KDM5CKDM4EKDM4CKDM2AKDM3A | |
| SCHEMBL70700 | 0.85 | KDM4C (0.78) | KDM5CKDM4EKDM4CKDM2AKDM3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117924171-A | Phenanthrone derivative and synthesis method thereof | 华南理工大学 | 2024-04-26 | — | — | CN | claimed |
| CN-114874127-B | Preparation method of difluoro carbonyl indolone compound | 中国药科大学 | 2023-06-09 | — | — | CN | claimed |
| CN-114874127-A | Preparation method of difluorocarbonylation indolone compound | 中国药科大学 | 2022-08-09 | — | — | CN | claimed |
| CN-113512068-B | Double-ligand nitrosyl ruthenium complex and preparation method and application thereof | 山西大学 | 2022-05-31 | — | — | CN | claimed |
| CN-119948027-A | SOS1 protein degradation agent and application thereof | 领泰生物医药(绍兴)有限公司 | 2025-05-06 | — | — | CN | disclosed |
| CN-115677569-B | Synthesis method of pyridines and substituted benzenes based on reduction coupling reaction of iron-catalyzed aryl halide and alkyl halide | 重庆大学 | 2024-05-28 | — | — | CN | disclosed |
| CN-115141138-B | Method for constructing fluoride by decarboxylation of alkyl carboxylic acid | 中山大学 | 2023-11-28 | — | — | CN | disclosed |
| CN-114832862-B | Catalytic composition for coupling reaction and application of catalytic composition in preparation of isoquinoline-1, 3-dione compounds | 中国药科大学 | 2023-06-30 | — | — | CN | disclosed |
| CN-114874127-B | Preparation method of difluoro carbonyl indolone compound | 中国药科大学 | 2023-06-09 | — | — | CN | disclosed |
| CN-115677569-A | Pyridine and substituted benzene compound synthesis method based on iron-catalyzed reduction coupling reaction of aryl halide and alkyl halide | 重庆大学 | 2023-02-03 | — | — | CN | disclosed |
| CN-115141138-A | Method for constructing fluoride by decarboxylation of alkyl carboxylic acid | 中山大学 | 2022-10-04 | — | — | CN | disclosed |
| CN-113512068-B | Double-ligand nitrosyl ruthenium complex and preparation method and application thereof | 山西大学 | 2022-05-31 | — | — | CN | disclosed |
| CN-113512068-B | Double-ligand nitrosyl ruthenium complex and preparation method and application thereof | 山西大学 | 2022-05-31 | — | — | CN | disclosed |