SCHEMBL29670840

SCHEMBL29670840

CC(C)=CCCC(C)=CCCC1(C)CCc2c(C)c(O)c(C)c(C)c2O1

nearest known ligand 0.82

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 18/20 0.82
PSEN1 P49768 1/20 0.52
MAPT P10636 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Alpha-Tocotrienol SCHEMBL29439361 1.00 ALOX5 (0.82) ALOX5PSEN1MAPT
SCHEMBL29838335 1.00 ALOX5 (0.82) ALOX5PSEN1MAPT
Alpha-Tocotrienol SCHEMBL29670863 1.00 ALOX5 (0.82) ALOX5PSEN1MAPT
SCHEMBL23167044 1.00 ALOX5 (0.82) ALOX5PSEN1MAPT
Alpha-Tocotrienol SCHEMBL2364445 1.00 ALOX5 (0.82) ALOX5PSEN1MAPT
SCHEMBL23166910 1.00 ALOX5 (0.82) ALOX5PSEN1MAPT
Alpha-Tocotrienol SCHEMBL31053049 1.00 ALOX5 (0.82) ALOX5PSEN1MAPT
SCHEMBL23166911 1.00 ALOX5 (0.82) ALOX5PSEN1MAPT
SCHEMBL29838380 1.00 ALOX5 (0.82) ALOX5PSEN1MAPT
Alpha-Tocotrienol SCHEMBL242672 1.00 ALOX5 (0.82) ALOX5PSEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114746430-A Quinone-, hydroquinone-and naphthoquinone-analogues of vattinoquinone for the treatment of mitochondrial disorders 康德生物医疗有限公司 2022-07-12 CN disclosed