Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 5/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 3/20 | 0.46 |
| ▸ | HTR2B | P41595 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3613788 | 1.00 | IDO1 (0.55) | IDO1LMNAALDH1A1GAAMAPT | |
| SCHEMBL3264403 | 0.95 | IDO1 (0.56) | IDO1LMNAALDH1A1GAAMAPT | |
| SCHEMBL19760706 | 0.89 | IDO1 (0.59) | IDO1LMNAALDH1A1GAAMAPT | |
| SCHEMBL29611992 | 0.89 | IDO1 (0.59) | IDO1LMNAALDH1A1GAAMAPT | |
| SCHEMBL28104371 | 0.81 | IDO1 (0.54) | IDO1LMNAALDH1A1GAAMAPT | |
| SCHEMBL29671039 | 0.80 | IDO1 (0.59) | IDO1LMNAGAAKDM4E | |
| SCHEMBL29671044 | 0.80 | IDO1 (0.59) | IDO1LMNAALDH1A1GAAMAPT | |
| SCHEMBL28543985 | 0.80 | IDO1 (0.59) | IDO1LMNAALDH1A1PDE4DKDM4E | |
| SCHEMBL29671036 | 0.80 | IDO1 (0.59) | IDO1LMNAALDH1A1PDE4DKDM4E | |
| SCHEMBL28770996 | 0.80 | IDO1 (0.59) | IDO1LMNAGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117003738-A | Imidazole spiro compound and synthesis method thereof | 湘潭大学 | 2023-11-07 | — | — | CN | claimed |
| CN-115433186-A | 4, 5-dihydro-3H-pyrrolo [2,3-c ] quinoline compound and synthetic method thereof | 湘潭大学 | 2022-12-06 | — | — | CN | claimed |
| CN-114539266-A | Maleimidocarbazole compound and synthesis method thereof | 湘潭大学 | 2022-05-27 | — | — | CN | claimed |
| CN-119019336-A | 4-Hydroxy-5-phenylaminoimidazole compound, and preparation method and application thereof | 浙大城市学院 | 2024-11-26 | — | — | CN | disclosed |
| CN-117003738-A | Imidazole spiro compound and synthesis method thereof | 湘潭大学 | 2023-11-07 | — | — | CN | disclosed |
| CN-117003738-A | Imidazole spiro compound and synthesis method thereof | 湘潭大学 | 2023-11-07 | — | — | CN | disclosed |
| CN-115433186-A | 4, 5-dihydro-3H-pyrrolo [2,3-c ] quinoline compound and synthetic method thereof | 湘潭大学 | 2022-12-06 | — | — | CN | disclosed |
| CN-115433186-A | 4, 5-dihydro-3H-pyrrolo [2,3-c ] quinoline compound and synthetic method thereof | 湘潭大学 | 2022-12-06 | — | — | CN | disclosed |
| CN-114539266-A | Maleimidocarbazole compound and synthesis method thereof | 湘潭大学 | 2022-05-27 | — | — | CN | disclosed |
| CN-114539266-A | Maleimidocarbazole compound and synthesis method thereof | 湘潭大学 | 2022-05-27 | — | — | CN | disclosed |