Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 3/20 | 0.56 |
| ▸ | IDH1 | O75874 | 1/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | APLNR | P35414 | 3/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15886669 | 1.00 | BTK (0.56) | BTKIDH1DDB1CRBNAPLNR | |
| SCHEMBL12075530 | 0.82 | MEN1 (0.36) | BTK | |
| SCHEMBL12598648 | 0.80 | CCR1 (0.37) | BTK | |
| SCHEMBL12598652 | 0.80 | CCR1 (0.37) | BTK | |
| SCHEMBL6982246 | 0.77 | CCR1 (0.54) | BTKTGFBR1 | |
| SCHEMBL3155981 | 0.75 | BTK (0.61) | BTKIDH1DDB1CRBNAPLNR | |
| SCHEMBL30433661 | 0.74 | ASIC3 (0.46) | IDH1 | |
| SCHEMBL20557572 | 0.74 | ASIC3 (0.46) | IDH1 | |
| SCHEMBL19919698 | 0.73 | BTK (0.31) | BTKTGFBR1 | |
| SCHEMBL732877 | 0.73 | BTK (0.34) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114585625-A | Triazolopyrimidines as A2A/A2B inhibitors | 因赛特公司 | 2022-06-03 | — | — | CN | disclosed |