Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 2/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 2/20 | 1.00 |
| ▸ | HIF1A | Q16665 | 1/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.97 |
| ▸ | EGFR | P00533 | 8/20 | 0.60 |
| ▸ | KDR | P35968 | 8/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | GOT1 | P17174 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MPO | P05164 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Todralazine SCHEMBL49644 | 1.00 | LMNA (1.00) | LMNACYP1A2CYP2D6HIF1ATDP1 | |
| Todralazine SCHEMBL211261 | 0.99 | TDP1 (1.00) | LMNACYP1A2CYP2D6HIF1ATDP1 | |
| Todralazine SCHEMBL1417412 | 0.97 | TDP1 (0.97) | LMNACYP1A2CYP2D6HIF1ATDP1 | |
| SCHEMBL31506911 | 0.80 | LMNA (0.67) | LMNACYP1A2CYP2D6HIF1ATDP1 | |
| SCHEMBL12106741 | 0.77 | LMNA (0.62) | LMNACYP1A2CYP2D6HIF1ATDP1 | |
| SCHEMBL14543960 | 0.77 | EGFR (0.63) | LMNACYP1A2CYP2D6HIF1ATDP1 | |
| SCHEMBL12765309 | 0.77 | LMNA (0.61) | LMNACYP1A2CYP2D6HIF1ATDP1 | |
| SCHEMBL28900093 | 0.74 | NPC1 (0.71) | LMNACYP1A2CYP2D6HIF1ATDP1 | |
| SCHEMBL8842155 | 0.74 | CYP1A2 (0.58) | LMNACYP1A2CYP2D6HIF1ATDP1 | |
| SCHEMBL18607384 | 0.74 | LMNA (0.58) | LMNACYP1A2CYP2D6HIF1ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11814673-B2 | Cardiovascular disease | GENINCODE PLC (GB) | 2023-11-14 | — | — | US | disclosed |
| CN-114561277-A | Methods and devices for conditioning cell populations for cell therapy | 得克萨斯州大学系统董事会 | 2022-05-31 | — | — | CN | disclosed |