SCHEMBL29673192

SCHEMBL29673192

c1ccc2c(c1)ncc1cccn12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 1.00
ALDH1A1 P00352 8/20 1.00
HPGD P15428 4/20 1.00
HSD17B10 Q99714 4/20 1.00
GAA P10253 2/20 1.00
GLA P06280 1/20 1.00
MAPT P10636 4/20 0.47
TDP1 Q9NUW8 4/20 0.47
PTPN1 P18031 2/20 0.47
CHEK1 O14757 1/20 0.47
LIMK1 P53667 1/20 0.47
MAPK14 Q16539 1/20 0.47
PTPN2 P17706 1/20 0.47
KMT2A Q03164 6/20 0.46
MEN1 O00255 5/20 0.46
MAPK1 P28482 4/20 0.46
RAB9A P51151 4/20 0.46
NPC1 O15118 3/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
ATM Q13315 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1078583 1.00 KDM4E (1.00) KDM4EALDH1A1HPGDHSD17B10GAA
Carbon Dioxide SCHEMBL30932543 0.93 KDM4E (0.86) KDM4EALDH1A1HPGDHSD17B10GAA
Benzoquinone SCHEMBL30677004 0.90 KDM4E (0.81) KDM4EALDH1A1HPGDHSD17B10GAA
SCHEMBL29126970 0.80 KDM4E (0.67) KDM4EALDH1A1HPGDHSD17B10GAA
SCHEMBL31251989 0.79 KDM4E (0.66) KDM4EALDH1A1HPGDHSD17B10GAA
SCHEMBL29229082 0.78 KDM4E (0.63) KDM4EALDH1A1HPGDHSD17B10GAA
SCHEMBL31612336 0.77 ALDH1A1 (0.62) KDM4EALDH1A1HPGDHSD17B10GAA
SCHEMBL29229124 0.77 ALDH1A1 (0.62) KDM4EALDH1A1HPGDHSD17B10GAA
SCHEMBL30932617 0.77 KDM4E (0.62) KDM4EALDH1A1HPGDHSD17B10GAA
SCHEMBL31612371 0.77 ALDH1A1 (0.62) KDM4EALDH1A1HPGDHSD17B10GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120118090-A (E) Process for preparing (E) -3- (pyrrolo [1,2-a ] quinoxalin-3-yl) acrylic esters and derivatives thereof 石河子大学 2025-06-10 CN claimed
CN-120118091-A Preparation method of 1-chloropyrrolo [1,2-a ] quinoxaline and derivatives thereof 石河子大学 2025-06-10 CN claimed
CN-119390699-A Synthesis method of pyrrolo [1,2-a ] quinoxaline-4 (5H) -ketone compound 重庆文理学院 2025-02-07 CN claimed
CN-118374812-A Method for preparing pyrrolo [1,2-a ] quinoxaline compound through electrocatalytic reaction 宁夏医科大学 2024-07-23 CN claimed
CN-118184588-A N-aryl/alkyl quinazolinone compound and synthesis method thereof 陕西科技大学 2024-06-14 CN claimed
CN-118184632-A Pyrrolo [1,2-a ] quinoxaline compound synthesized from aminopyrrole arene and carbon dioxide and synthesis method thereof 陕西科技大学 2024-06-14 CN claimed
CN-117230460-A Method for electrocatalytic synthesis of pyrrolo [1,2-a ] quinoxaline derivative 宁夏医科大学 2023-12-15 CN claimed
CN-117143104-A Pyrrolo [1,2-a ] quinoxaline compound synthesized from nitropyrrole aromatic hydrocarbon and carbon dioxide and synthesis method thereof 陕西科技大学 2023-12-01 CN claimed
CN-114560862-A Synthesis method of pyrrolo [1,2-A ] quinoxaline-4 (5H) -ketone and derivative thereof 山东龙辰药业有限公司 2022-05-31 CN claimed
CN-119219641-B Preparation method and application of aza-arene compound synthesized by photocatalysis 华南理工大学 2026-05-19 CN disclosed
CN-119219641-B Preparation method and application of aza-arene compound synthesized by photocatalysis 华南理工大学 2026-05-19 CN disclosed
WO-2026090116-A2 RAS INHIBITORS Revolution Medicines, Inc. (US) 2026-04-30 WO disclosed
CN-117143104-B Pyrrolo [1,2-a ] quinoxaline compound synthesized from nitropyrrole aromatic hydrocarbon and carbon dioxide and synthesis method thereof 陕西科技大学 2026-04-10 CN disclosed
CN-120865216-A Method for preparing 4-aralkyl thioether pyrrolo [1,2-a ] quinoxaline derivative 宁夏医科大学 2025-10-31 CN disclosed
CN-116082344-A Phenyl butanone substituted pyrrolo [1,2-a ] quinoxaline compound and preparation method thereof 宁夏医科大学 2023-05-09 CN disclosed
CN-115677708-A Preparation method of pyrroloquinoxaline 五邑大学 2023-02-03 CN disclosed
CN-115368362-A Quinoxalinone derivatives as BTK inhibitors and application thereof 华东理工大学 2022-11-22 CN disclosed
CN-115322200-A Preparation method of spiro pyrroloquinoxaline derivative 五邑大学 2022-11-11 CN disclosed
CN-114560862-A Synthesis method of pyrrolo [1,2-A ] quinoxaline-4 (5H) -ketone and derivative thereof 山东龙辰药业有限公司 2022-05-31 CN disclosed
CN-114560862-A Synthesis method of pyrrolo [1,2-A ] quinoxaline-4 (5H) -ketone and derivative thereof 山东龙辰药业有限公司 2022-05-31 CN disclosed