Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 3/20 | 0.40 |
| ▸ | SKP1 | P63208 | 3/20 | 0.40 |
| ▸ | SKP2 | Q13309 | 3/20 | 0.40 |
| ▸ | CNR1 | P21554 | 8/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.36 |
| ▸ | ACACB | O00763 | 3/20 | 0.36 |
| ▸ | ACACA | Q13085 | 3/20 | 0.36 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29070067 | 1.00 | CKS1B (0.40) | CKS1BSKP1SKP2CNR1L3MBTL1 | |
| SCHEMBL23731714 | 0.88 | BRD4 (0.40) | CKS1BSKP1SKP2ACACBACACA | |
| SCHEMBL30103140 | 0.88 | BRD4 (0.40) | CKS1BSKP1SKP2ACACBACACA | |
| SCHEMBL31396177 | 0.88 | CKS1B (0.36) | CKS1BSKP1SKP2ACACBACACA | |
| SCHEMBL31401524 | 0.87 | CKS1B (0.34) | CKS1BSKP1SKP2L3MBTL1ACACB | |
| SCHEMBL23706015 | 0.87 | L3MBTL1 (0.41) | CKS1BSKP1SKP2L3MBTL1ACACB | |
| SCHEMBL26970021 | 0.86 | CNR1 (0.43) | CNR1ADORA2AADORA1PIM1PIM2 | |
| SCHEMBL31401234 | 0.86 | EGLN1 (0.35) | CKS1BSKP1SKP2ACACBACACA | |
| SCHEMBL30689837 | 0.85 | CNR1 (0.38) | CNR1PIM1PIM2 | |
| SCHEMBL31396029 | 0.85 | RET (0.38) | CKS1BSKP1SKP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4244213-A1 | COMPOUNDS AND USES THEREOF | Foghorn Therapeutics Inc. (US) | 2023-09-20 | — | — | EP | disclosed |
| WO-2022103899-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2022-05-19 | — | — | WO | disclosed |