SCHEMBL2967396

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5543735	0.82	HPGD (0.61)	MLYCDALDH1A1HPGDMAPTHSP90AA1
	SCHEMBL1004360	0.81	MLYCD (0.62)	MLYCDALDH1A1HPGDMAPTLPAR1
	SCHEMBL5543209	0.76	MLYCD (0.62)	MLYCDALDH1A1HPGDMAPTL3MBTL1
	SCHEMBL12482771	0.75	HPGD (0.54)	MLYCDALDH1A1HPGDMAPTLMNA
	SCHEMBL3456913	0.74	MLYCD (0.54)	MLYCDALDH1A1MAPTLPAR1LPAR5
	SCHEMBL11218358	0.74	TSHR (0.57)	MLYCDHPGDSLC6A9HSP90AA1HSP90AB1
	SCHEMBL3099164	0.74	MLYCD (1.00)	MLYCDSMN1; SMN2
	SCHEMBL1003664	0.73	HPGD (0.69)	MLYCDALDH1A1HPGDMAPTL3MBTL1
	SCHEMBL97482	0.73	EGFR (0.60)	MLYCDALDH1A1HPGD
	SCHEMBL16308028	0.73	MLYCD (0.53)	MLYCDALDH1A1HPGDSLC6A9HSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.