SCHEMBL29674530

SCHEMBL29674530

COc1ccc(C(OC[C@@H]2O[C@@H](n3cnc4c(NC(=O)c5ccccc5)ncnc43)C[C@H]2O)(c2ccccc2)c2ccc(OC)cc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TYMP P19971 3/20 0.58
P2RY12 Q9H244 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3824084 1.00 TYMP (0.58) TYMPP2RY12
SCHEMBL21044306 1.00 TYMP (0.58) TYMPP2RY12
SCHEMBL31556050 1.00 TYMP (0.58) TYMPP2RY12
SCHEMBL29674456 1.00 TYMP (0.58) TYMPP2RY12
SCHEMBL29674438 1.00 TYMP (0.58) TYMPP2RY12
SCHEMBL22984001 1.00 TYMP (0.58) TYMPP2RY12
SCHEMBL3824088 1.00 TYMP (0.58) TYMPP2RY12
SCHEMBL29720432 0.95 TYMP (0.63) TYMPP2RY12
SCHEMBL11040442 0.95 TYMP (0.63) TYMPP2RY12
SCHEMBL31093231 0.93 TYMP (0.49) TYMPP2RY12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4013428-A1 MODIFIED OLIGOMERIC COMPOUNDS AND USES THEREOF Ionis Pharmaceuticals, Inc. (US) 2022-06-22 EP disclosed