SCHEMBL31093231

SCHEMBL31093231

COc1ccc(C(OC[C@H]2O[C@@H](n3cnc4c(NC(=O)c5ccccc5)ncnc43)CC[C@@H]2O)(c2ccccc2)c2ccc(OC)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ TYMP P19971 6/20 0.49
▸ P2RY12 Q9H244 1/20 0.42
▸ ADORA2A P29274 1/20 0.42
▸ ADORA2B P29275 1/20 0.42
▸ BMPR1B O00238 1/20 0.41
▸ ADORA1 P30542 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21044306 0.93 TYMP (0.58) TYMPP2RY12
SCHEMBL29674456 0.93 TYMP (0.58) TYMPP2RY12
SCHEMBL29674438 0.93 TYMP (0.58) TYMPP2RY12
SCHEMBL31556050 0.93 TYMP (0.58) TYMPP2RY12
SCHEMBL29674530 0.93 TYMP (0.58) TYMPP2RY12
SCHEMBL22984001 0.93 TYMP (0.58) TYMPP2RY12
SCHEMBL3824084 0.93 TYMP (0.58) TYMPP2RY12
SCHEMBL3824088 0.93 TYMP (0.58) TYMPP2RY12
SCHEMBL20691448 0.90 TYMP (0.46) TYMPP2RY12ADORA2AADORA2BADORA1
SCHEMBL21158501 0.90 TYMP (0.46) TYMPP2RY12ADORA2AADORA2BADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4673453-A1 DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS FOR RNA INTERFERENCE AND METHODS RELATING THERETO Wave Life Sciences Ltd. (SG) 2026-01-07 — — EP disclosed
US-20250382617-A1 DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS FOR RNA INTERFERENCE AND METHODS RELATING THERETO WAVE LIFE SCIENCES LTD. (SG) 2025-12-18 — — US disclosed
WO-2024182749-A1 DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS FOR RNA INTERFERENCE AND METHODS RELATING THERETO WAVE LIFE SCIENCES LTD. (SG) 2024-09-06 — — WO disclosed
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