Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 5/20 | 1.00 |
| ▸ | BRAF | P15056 | 13/20 | 0.77 |
| ▸ | EGFR | P00533 | 11/20 | 0.73 |
| ▸ | CSF1R | P07333 | 1/20 | 0.67 |
| ▸ | ABL1 | P00519 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29493482 | 1.00 | KIT (1.00) | KITBRAFEGFRCSF1RABL1 | |
| SCHEMBL588975 | 1.00 | KIT (1.00) | KITBRAFEGFRCSF1RABL1 | |
| SCHEMBL588917 | 0.96 | KIT (0.93) | KITBRAFEGFRCSF1R | |
| SCHEMBL590507 | 0.93 | KIT (0.86) | KITBRAFEGFRABL1 | |
| SCHEMBL16236899 | 0.92 | KIT (0.86) | KITBRAFEGFR | |
| SCHEMBL27933497 | 0.91 | KIT (0.84) | KITBRAFEGFRCSF1R | |
| SCHEMBL12871531 | 0.91 | KIT (0.84) | KITBRAFEGFRABL1 | |
| SCHEMBL12988951 | 0.91 | KIT (0.83) | KITBRAFEGFR | |
| SCHEMBL19500735 | 0.90 | KIT (0.82) | KITBRAFEGFRCSF1R | |
| SCHEMBL4100085 | 0.90 | KIT (0.81) | KITBRAFEGFRABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3246327-B1 | 3-ACETYLENYL-PYRAZOLE-PYRIMIDINE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USES THEREOF | SI CHUAN UNIV (CN) | 2022-11-23 | — | — | EP | disclosed |