SCHEMBL2967510

SCHEMBL2967510

CCCCc1ccc(-c2c(C)cc(Br)c3c2CC=C3)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SKP2 Q13309 1/20 0.38
HSD11B1 P28845 2/20 0.35
SMN1; SMN2 Q16637 4/20 0.34
RARB P10826 3/20 0.34
NPC1 O15118 3/20 0.34
RAB9A P51151 3/20 0.34
NFKB1 P19838 2/20 0.34
NFKB2 Q00653 2/20 0.34
RELA Q04206 2/20 0.34
MAPK1 P28482 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
NISCH Q9Y2I1 1/20 0.34
CA2 P00918 2/20 0.33
GPR84 Q9NQS5 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
CYP4Z1 Q86W10 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2969922 0.90 SKP2 (0.38) SKP2HSD11B1SMN1; SMN2RARBNPC1
SCHEMBL2970614 0.90 SKP2 (0.38) SKP2HSD11B1SMN1; SMN2RARBNPC1
SCHEMBL2965580 0.81 MEN1 (0.36) SMN1; SMN2ALDH1A1MAPT
SCHEMBL2963891 0.80 SKP2 (0.38) SKP2HSD11B1SMN1; SMN2RARBNPC1
SCHEMBL2972633 0.78 MEN1 (0.32) CYP1A2ALDH1A1
SCHEMBL2967504 0.78 MAOA (0.32)
SCHEMBL2972478 0.78 SKP2 (0.38) SKP2HSD11B1SMN1; SMN2RARBNPC1
SCHEMBL2964501 0.78 SKP2 (0.38) SKP2HSD11B1SMN1; SMN2RARBNPC1
SCHEMBL2973419 0.78 SKP2 (0.38) SKP2HSD11B1SMN1; SMN2RARBNPC1
SCHEMBL2966698 0.78 SKP2 (0.35) SKP2HSD11B1SMN1; SMN2RARBNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7763562-B2 Heteroatom bridged metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2010-07-27 US disclosed
US-20070135597-A1 Heteroatom bridged metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. 2007-06-14 US disclosed
WO-2006065809-A2 HETEROATOM BRIDGED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2006-06-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070135597-A1 Heteroatom bridged metallocene compounds for olefin polymerization AP2M1, AP1M1, PYM1 SKP2 2873/4885HSD11B1 4377/4885SMN1; SMN2 4156/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.