Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 13/20 | 0.54 |
| ▸ | HTR2A | P28223 | 8/20 | 0.54 |
| ▸ | HTR1A | P08908 | 7/20 | 0.54 |
| ▸ | DRD3 | P35462 | 7/20 | 0.50 |
| ▸ | FAAH | O00519 | 2/20 | 0.50 |
| ▸ | DRD4 | P21917 | 4/20 | 0.49 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28612063 | 1.00 | DRD2 (0.54) | DRD2HTR2AHTR1ADRD3FAAH | |
| SCHEMBL29675345 | 0.94 | DRD2 (0.51) | DRD2HTR2AHTR1ADRD3FAAH | |
| SCHEMBL28615753 | 0.94 | DRD2 (0.51) | DRD2HTR2AHTR1ADRD3FAAH | |
| SCHEMBL29675647 | 0.93 | DRD2 (0.55) | DRD2HTR2AHTR1ADRD3FAAH | |
| SCHEMBL28612182 | 0.93 | DRD2 (0.55) | DRD2HTR2AHTR1ADRD3FAAH | |
| SCHEMBL28615750 | 0.90 | DRD2 (0.53) | DRD2HTR2AHTR1ADRD3FAAH | |
| SCHEMBL28614767 | 0.90 | DRD2 (0.53) | DRD2HTR2AHTR1ADRD3FAAH | |
| SCHEMBL29675349 | 0.90 | DRD2 (0.53) | DRD2HTR2AHTR1ADRD3FAAH | |
| SCHEMBL29675501 | 0.90 | DRD2 (0.53) | DRD2HTR2AHTR1ADRD3FAAH | |
| SCHEMBL29675111 | 0.87 | DRD2 (0.53) | DRD2HTR2AHTR1ADRD3FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113292515-B | Urea compound containing piperazine group and preparation method and application thereof | 沈阳药科大学 | 2022-05-20 | — | — | CN | claimed |
| CN-113292515-B | Urea compound containing piperazine group and preparation method and application thereof | 沈阳药科大学 | 2022-05-20 | — | — | CN | disclosed |