SCHEMBL29675229

SCHEMBL29675229

Clc1ccc2oc3c(I)cccc3c2c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 9/20 0.56
ALDH1A1 P00352 2/20 0.46
LMNA P02545 1/20 0.46
KMT2A Q03164 1/20 0.46
GPR55 Q9Y2T6 1/20 0.46
CDC7 O00311 1/20 0.43
DYRK3 O43781 1/20 0.43
IGF1R P08069 1/20 0.43
PIM1 P11309 1/20 0.43
CLK2 P49760 1/20 0.43
GSK3A P49840 1/20 0.43
GSK3B P49841 1/20 0.43
CSNK2A1 P68400 1/20 0.43
DYRK1A Q13627 1/20 0.43
PKN2 Q16513 1/20 0.43
PIM3 Q86V86 1/20 0.43
CLK4 Q9HAZ1 1/20 0.43
PIM2 Q9P1W9 1/20 0.43
GABRP O00591 4/20 0.42
GABRD O14764 4/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2287518 0.82 AHR (0.64) AHRALDH1A1LMNAKMT2AGPR55
SCHEMBL12610225 0.82 PTPRF (0.41) AHRALDH1A1KMT2APIM1PIM3
SCHEMBL21191630 0.79 AHR (0.56) AHRALDH1A1LMNAKMT2AGPR55
SCHEMBL20754180 0.79 AHR (0.56) AHRALDH1A1LMNAKMT2AGPR55
SCHEMBL2958772 0.79 AHR (0.56) AHRALDH1A1LMNAKMT2AGPR55
SCHEMBL30138112 0.79 PIM1 (0.43) CDC7PIM1CSNK2A1PIM3PIM2
SCHEMBL18820608 0.79 PIM1 (0.43) CDC7PIM1CSNK2A1PIM3PIM2
SCHEMBL18830910 0.79 KDM4E (0.42) ALDH1A1LMNAKMT2AKDM4EHPGD
SCHEMBL24090334 0.79 AHR (0.67) AHRALDH1A1LMNAKMT2AGPR55
SCHEMBL2521186 0.77 ALOX5 (0.46) AHRALDH1A1LMNAKMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022149757-A1 NOVEL HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME 주식회사 센텀머티리얼즈 2022-07-14 WO disclosed