Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 9/20 | 0.62 |
| ▸ | BCR | P11274 | 6/20 | 0.59 |
| ▸ | KIT | P10721 | 5/20 | 0.56 |
| ▸ | LCK | P06239 | 3/20 | 0.55 |
| ▸ | CSF1R | P07333 | 2/20 | 0.55 |
| ▸ | LYN | P07948 | 2/20 | 0.55 |
| ▸ | FYN | P06241 | 1/20 | 0.55 |
| ▸ | YES1 | P07947 | 1/20 | 0.55 |
| ▸ | HCK | P08631 | 1/20 | 0.55 |
| ▸ | FGR | P09769 | 1/20 | 0.55 |
| ▸ | SRC | P12931 | 1/20 | 0.55 |
| ▸ | CSK | P41240 | 1/20 | 0.55 |
| ▸ | BLK | P51451 | 1/20 | 0.55 |
| ▸ | BMX | P51813 | 1/20 | 0.55 |
| ▸ | SRMS | Q9H3Y6 | 1/20 | 0.55 |
| ▸ | TEK | Q02763 | 2/20 | 0.54 |
| ▸ | KDR | P35968 | 2/20 | 0.54 |
| ▸ | MAP3K7 | O43318 | 2/20 | 0.53 |
| ▸ | MAP4K2 | Q12851 | 2/20 | 0.53 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29675215 | 0.97 | ABL1 (0.65) | ABL1BCRKITLCKCSF1R | |
| SCHEMBL24626405 | 0.97 | ABL1 (0.65) | ABL1BCRKITLCKCSF1R | |
| SCHEMBL2966570 | 0.89 | ABL1 (0.72) | ABL1BCRKITLCKCSF1R | |
| SCHEMBL29675250 | 0.89 | ABL1 (0.54) | ABL1BCRKITLCKCSF1R | |
| SCHEMBL24626401 | 0.89 | ABL1 (0.54) | ABL1BCRKITLCKCSF1R | |
| SCHEMBL24626004 | 0.85 | DDR1 (0.72) | ABL1BCRKITSRCDDR1 | |
| SCHEMBL29675181 | 0.85 | DDR1 (0.72) | ABL1BCRKITSRCDDR1 | |
| SCHEMBL24626053 | 0.84 | ABL1 (0.63) | ABL1BCRKITLCKCSF1R | |
| SCHEMBL29675171 | 0.84 | ABL1 (0.63) | ABL1BCRKITLCKCSF1R | |
| SCHEMBL24626014 | 0.83 | ABL1 (0.62) | ABL1BCRKITLCKCSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022149855-A1 | HETEROARYL-ETHYNYL DERIVATIVE COMPOUND AND USE THEREOF | 주식회사 비투에스바이오 | 2022-07-14 | — | — | WO | claimed |
| WO-2022149855-A1 | HETEROARYL-ETHYNYL DERIVATIVE COMPOUND AND USE THEREOF | 주식회사 비투에스바이오 | 2022-07-14 | — | — | WO | disclosed |