Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.62 |
| ▸ | GFER | P55789 | 4/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | REV1 | Q9UBZ9 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28631507 | 1.00 | RXFP1 (0.62) | RXFP1GFERNPC1LMNASMN1; SMN2 | |
| SCHEMBL29675413 | 0.97 | RXFP1 (0.58) | RXFP1GFERNPC1LMNASMN1; SMN2 | |
| SCHEMBL28624586 | 0.97 | RXFP1 (0.58) | RXFP1GFERNPC1LMNASMN1; SMN2 | |
| SCHEMBL28627158 | 0.93 | RXFP1 (0.55) | RXFP1GFERNPC1LMNASMN1; SMN2 | |
| SCHEMBL29675429 | 0.93 | RXFP1 (0.55) | RXFP1GFERNPC1LMNASMN1; SMN2 | |
| SCHEMBL29675301 | 0.93 | RXFP1 (0.57) | RXFP1GFERNPC1LMNASMN1; SMN2 | |
| SCHEMBL28616264 | 0.93 | RXFP1 (0.57) | RXFP1GFERNPC1LMNASMN1; SMN2 | |
| SCHEMBL29675280 | 0.90 | LMNA (0.54) | RXFP1GFERNPC1LMNASMN1; SMN2 | |
| SCHEMBL28624564 | 0.90 | LMNA (0.54) | RXFP1GFERNPC1LMNASMN1; SMN2 | |
| SCHEMBL29675324 | 0.88 | GFER (0.59) | RXFP1GFERNPC1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113292515-B | Urea compound containing piperazine group and preparation method and application thereof | 沈阳药科大学 | 2022-05-20 | — | — | CN | claimed |
| CN-113292515-B | Urea compound containing piperazine group and preparation method and application thereof | 沈阳药科大学 | 2022-05-20 | — | — | CN | disclosed |