Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | RAF1 | P04049 | 3/20 | 0.44 |
| ▸ | BRAF | P15056 | 3/20 | 0.44 |
| ▸ | ACACB | O00763 | 7/20 | 0.44 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.42 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29676386 | 0.87 | HRH4 (0.44) | MAPK1ACACBLRRK2 | |
| SCHEMBL29676029 | 0.86 | PIK3CA (0.50) | PIK3CAMAPK1RAF1BRAFSHMT2 | |
| SCHEMBL29675876 | 0.82 | ACACB (0.49) | MAPK1ACACB | |
| SCHEMBL29675982 | 0.82 | ACACB (0.49) | MAPK1ACACB | |
| SCHEMBL29675718 | 0.78 | ACACB (0.52) | MAPK1ACACB | |
| SCHEMBL29676091 | 0.78 | ACACB (0.52) | MAPK1ACACB | |
| SCHEMBL18931264 | 0.77 | PIK3CA (0.51) | PIK3CALRRK2TRPV3 | |
| SCHEMBL29676120 | 0.77 | ACACB (0.48) | ACACB | |
| SCHEMBL1911474 | 0.77 | PIK3CA (0.54) | PIK3CARAF1BRAFLRRK2 | |
| SCHEMBL18704867 | 0.76 | PIK3CA (0.52) | PIK3CALRRK2TRPV3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108617166-B | Protein kinase inhibitor benzolactam compounds | 大冢制药株式会社 | 2022-05-17 | — | — | CN | claimed |