Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 14/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.44 |
| ▸ | USP7 | Q93009 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29676091 | 1.00 | ACACB (0.52) | ACACBMAPK1HRH4HRH3USP7 | |
| SCHEMBL29675982 | 0.94 | ACACB (0.49) | ACACBMAPK1 | |
| SCHEMBL29675876 | 0.94 | ACACB (0.49) | ACACBMAPK1 | |
| SCHEMBL29676386 | 0.79 | HRH4 (0.44) | ACACBMAPK1HRH4 | |
| SCHEMBL29675604 | 0.78 | PIK3CA (0.52) | ACACBMAPK1 | |
| SCHEMBL29676278 | 0.78 | ACACB (0.51) | ACACBMAPK1HRH4HRH3 | |
| SCHEMBL29676192 | 0.78 | ACACB (0.51) | ACACBMAPK1HRH4HRH3 | |
| SCHEMBL18793569 | 0.78 | HRH4 (0.46) | HRH4HRH3USP7 | |
| SCHEMBL22971532 | 0.73 | HRH3 (0.42) | HRH4HRH3 | |
| SCHEMBL29675797 | 0.72 | ACACB (0.49) | ACACBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108617166-B | Protein kinase inhibitor benzolactam compounds | 大冢制药株式会社 | 2022-05-17 | — | — | CN | claimed |