Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.72 |
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 5/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.38 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15926179 | 0.84 | NPSR1 (1.00) | NPSR1ALOX15IRAK4KDM4EMAPT | |
| SCHEMBL14590053 | 0.82 | NPSR1 (0.47) | NPSR1ACACBHTR1AKDM4EITGB1 | |
| SCHEMBL13445249 | 0.80 | ALDH1A1 (0.53) | NPSR1HTR1AKDM4EMAPTNPC1 | |
| SCHEMBL4664171 | 0.78 | NPSR1 (0.79) | NPSR1ALOX15IRAK4NPC1RAB9A | |
| SCHEMBL6793428 | 0.77 | NPSR1 (0.77) | NPSR1ALOX15IRAK4KDM4EMAPT | |
| SCHEMBL17117536 | 0.77 | NPSR1 (0.77) | NPSR1ALOX15IRAK4KDM4EMAPT | |
| SCHEMBL15745622 | 0.77 | NPSR1 (0.77) | NPSR1ALOX15IRAK4KDM4EMAPT | |
| SCHEMBL2767293 | 0.77 | NPSR1 (0.77) | NPSR1ALOX15IRAK4KDM4EMAPT | |
| SCHEMBL9296950 | 0.76 | NPSR1 (0.70) | NPSR1ALOX15IRAK4KDM4EMAPT | |
| SCHEMBL2765756 | 0.76 | NPSR1 (0.70) | NPSR1ALOX15IRAK4KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108617166-B | Protein kinase inhibitor benzolactam compounds | 大冢制药株式会社 | 2022-05-17 | — | — | CN | claimed |