Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 12/20 | 0.59 |
| ▸ | THRB | P10828 | 3/20 | 0.46 |
| ▸ | EGFR | P00533 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SDCBP | O00560 | 1/20 | 0.42 |
| ▸ | SDC2 | P34741 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31592602 | 0.76 | MAPK1 (0.64) | MAPK1 | |
| SCHEMBL30225824 | 0.76 | MAPK1 (1.00) | MAPK1 | |
| SCHEMBL28764082 | 0.76 | MAPK1 (1.00) | MAPK1 | |
| SCHEMBL29675587 | 0.75 | MAPK1 (0.42) | MAPK1LMNA | |
| SCHEMBL20720319 | 0.75 | MAPK1 (1.00) | MAPK1 | |
| SCHEMBL30225767 | 0.75 | MAPK1 (1.00) | MAPK1 | |
| SCHEMBL18794706 | 0.75 | MAPK1 (1.00) | MAPK1 | |
| SCHEMBL18793294 | 0.74 | MAPK1 (1.00) | MAPK1 | |
| SCHEMBL18794256 | 0.74 | MAPK1 (1.00) | MAPK1 | |
| SCHEMBL31592658 | 0.74 | MAPK1 (0.62) | MAPK1THRBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108617166-B | Protein kinase inhibitor benzolactam compounds | 大冢制药株式会社 | 2022-05-17 | — | — | CN | claimed |