Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.47 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.46 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.46 |
| ▸ | PLOD1 | Q02809 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | KCNB1 | Q14721 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ACACB | O00763 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29675407 | 0.88 | MEN1 (0.56) | MEN1KMT2AGFERUSP2KCNQ3 | |
| SCHEMBL29675867 | 0.85 | MEN1 (0.45) | MEN1KMT2AGFERUSP2PLOD2 | |
| SCHEMBL29676228 | 0.81 | MAPK1 (0.42) | MEN1KMT2AGFERUSP2NPC1 | |
| SCHEMBL6626168 | 0.80 | MEN1 (0.47) | MEN1KMT2AGFERKCNQ3KCNQ2 | |
| SCHEMBL6858656 | 0.80 | MEN1 (0.47) | MEN1KMT2AGFERKCNQ3KCNQ2 | |
| SCHEMBL782021 | 0.80 | MEN1 (0.47) | MEN1KMT2AGFERKCNQ3KCNQ2 | |
| SCHEMBL24731946 | 0.79 | KCNB1 (0.49) | MEN1KMT2AGFERKCNQ3KCNQ2 | |
| SCHEMBL24731947 | 0.79 | KCNB1 (0.49) | MEN1KMT2AGFERKCNQ3KCNQ2 | |
| SCHEMBL30083121 | 0.79 | KCNB1 (0.49) | MEN1KMT2AGFERKCNQ3KCNQ2 | |
| SCHEMBL29676386 | 0.78 | HRH4 (0.44) | NPC1ACACBMAPK1GPR139 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108617166-B | Protein kinase inhibitor benzolactam compounds | 大冢制药株式会社 | 2022-05-17 | — | — | CN | claimed |