Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.45 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.45 |
| ▸ | PLOD1 | Q02809 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 5/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 3/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 3/20 | 0.40 |
| ▸ | CTSS | P25774 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29675856 | 0.85 | MEN1 (0.55) | MEN1KMT2AGFERPLOD2PLOD3 | |
| SCHEMBL23343854 | 0.82 | MAPK1 (0.40) | MEN1KMT2AMAPK1LMNACTSK | |
| SCHEMBL29675688 | 0.79 | MAPK1 (0.46) | MAPK1ROCK2NPC1RAB9A | |
| SCHEMBL25249650 | 0.79 | HTR2C (0.48) | PLOD2PLOD3PLOD1MAPK1LMNA | |
| SCHEMBL25241453 | 0.78 | CHRM2 (0.48) | MEN1KMT2AGFERPLOD2PLOD3 | |
| SCHEMBL29675407 | 0.77 | MEN1 (0.56) | MEN1KMT2AGFERCTSKUSP2 | |
| SCHEMBL23343788 | 0.75 | MAPK1 (0.45) | MAPK1NPC1RAB9A | |
| SCHEMBL18765697 | 0.75 | CYP26A1 (0.47) | MEN1KMT2AMAPK1LMNAROCK2 | |
| SCHEMBL31037006 | 0.75 | MAPK1 (0.46) | MEN1KMT2AMAPK1 | |
| SCHEMBL29751787 | 0.75 | MAPK1 (0.46) | MEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108617166-B | Protein kinase inhibitor benzolactam compounds | 大冢制药株式会社 | 2022-05-17 | — | — | CN | claimed |