Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | HPGD | P15428 | 6/20 | 0.49 |
| ▸ | IGLV6-57 | P01721 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 3/20 | 0.44 |
| ▸ | CA9 | Q16790 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3366173 | 0.87 | RAB9A (0.56) | RAB9ATDP1KDM4EALDH1A1HPGD | |
| SCHEMBL30839619 | 0.87 | RAB9A (0.56) | RAB9ATDP1KDM4EALDH1A1HPGD | |
| SCHEMBL29543574 | 0.87 | RAB9A (0.56) | RAB9ATDP1KDM4EALDH1A1HPGD | |
| SCHEMBL3321719 | 0.86 | KDM4E (0.44) | RAB9ATDP1KDM4EALDH1A1HPGD | |
| SCHEMBL14050123 | 0.85 | KDM4E (0.63) | RAB9ATDP1KDM4EALDH1A1HPGD | |
| SCHEMBL5672583 | 0.85 | KDM4E (0.44) | RAB9ATDP1KDM4EALDH1A1HPGD | |
| SCHEMBL19305830 | 0.80 | TDP1 (0.49) | RAB9ATDP1KDM4EALDH1A1HPGD | |
| SCHEMBL29543904 | 0.80 | RAB9A (0.64) | RAB9ATDP1KDM4EALDH1A1HPGD | |
| SCHEMBL1767417 | 0.80 | TDP1 (0.44) | RAB9ATDP1KDM4EALDH1A1HPGD | |
| SCHEMBL29543943 | 0.80 | KDM4E (0.70) | RAB9ATDP1KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2230312-A1 | Probe compound for detecting and isolating enzymes and means and methods using the same | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2010-09-22 | — | — | EP | disclosed |
| US-20060142171-A1 | Novel alkaline protease | FORSKARPATENT I SYD AB (SE) | 2006-06-29 | — | — | US | disclosed |
| EP-1611235-A1 | NOVEL ALKALINE PROTEASE | Forskarpatent i Syd AB (SE) | 2006-01-04 | — | — | EP | disclosed |
| WO-2004085639-A9 | NOVEL ALKALINE PROTEASE | FORSKARPATENT I SYD AB (SE) | 2005-11-10 | — | — | WO | disclosed |
| WO-2004085639-A1 | NOVEL ALKALINE PROTEASE | FORSKARPATENT I SYD AB (SE) | 2004-10-07 | — | — | WO | disclosed |