Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.37 |
| ▸ | KLK7 | P49862 | 6/20 | 0.37 |
| ▸ | KLK5 | Q9Y337 | 5/20 | 0.37 |
| ▸ | EDNRB | P24530 | 1/20 | 0.34 |
| ▸ | EDNRA | P25101 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.34 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18765792 | 1.00 | ALDH1A1 (0.38) | ALDH1A1TDP1USP30KLK7KLK5 | |
| SCHEMBL30681402 | 0.86 | KLK7 (0.38) | USP30KLK7KLK5EDNRBEDNRA | |
| SCHEMBL29338728 | 0.86 | KLK7 (0.39) | ALDH1A1USP30KLK7KLK5EDNRB | |
| SCHEMBL14279582 | 0.84 | ALDH1A1 (0.48) | ALDH1A1TDP1KLK7KLK5LMNA | |
| SCHEMBL30990928 | 0.83 | GAA (0.40) | ALDH1A1EDNRBEDNRAGABRA1GABRG2 | |
| SCHEMBL18765993 | 0.83 | GAA (0.40) | ALDH1A1EDNRBEDNRAGABRA1GABRG2 | |
| SCHEMBL17141593 | 0.82 | ALDH1A1 (0.41) | ALDH1A1EDNRBEDNRAGAATSHR | |
| SCHEMBL17141566 | 0.80 | USP30 (0.42) | ALDH1A1USP30KLK7KLK5EDNRB | |
| SCHEMBL29676652 | 0.80 | USP30 (0.42) | ALDH1A1USP30KLK7KLK5EDNRB | |
| SCHEMBL30990970 | 0.78 | KLK7 (0.34) | ALDH1A1USP30KLK7KLK5EDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114948963-B | Benzolactam compounds as protein kinase inhibitors | 大冢制药株式会社 | 2025-05-27 | — | — | CN | disclosed |
| EP-3365334-B1 | BENZOLACTAM COMPOUNDS AS PROTEIN KINASE INHIBITORS | OTSUKA PHARMA CO LTD (JP) | 2024-07-17 | — | — | EP | disclosed |
| CN-114948963-A | Protein kinase inhibitor benzolactam compounds | 大冢制药株式会社 | 2022-08-30 | — | — | CN | disclosed |
| CN-108617166-B | Protein kinase inhibitor benzolactam compounds | 大冢制药株式会社 | 2022-05-17 | — | — | CN | disclosed |