SCHEMBL29677403

SCHEMBL29677403

CCCCCCn1c2ccc(C=O)cc2c2cc(C=Cc3ccc(-c4ccc(N(c5ccccc5)c5ccccc5)cc4)cc3)ccc21

nearest known ligand 0.45

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PTGER4 P35408 3/20 0.45
CNR2 P34972 5/20 0.43
PSEN1 P49768 3/20 0.43
PSEN2 P49810 3/20 0.43
APH1B Q8WW43 3/20 0.43
NCSTN Q92542 3/20 0.43
APH1A Q96BI3 3/20 0.43
PSENEN Q9NZ42 3/20 0.43
MAPT P10636 2/20 0.41
TP53 P04637 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
ICMT O60725 1/20 0.41
KDM4E B2RXH2 1/20 0.39
RORA P35398 1/20 0.38
RORC P51449 1/20 0.38
RORB Q92753 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28576490 1.00 PTGER4 (0.45) PTGER4CNR2PSEN1PSEN2APH1B
SCHEMBL29677283 0.97 PTGER4 (0.47) PTGER4CNR2PSEN1PSEN2APH1B
SCHEMBL28570847 0.97 PTGER4 (0.47) PTGER4CNR2PSEN1PSEN2APH1B
SCHEMBL28576341 0.94 ICMT (0.47) PTGER4CNR2PSEN1PSEN2APH1B
SCHEMBL29677367 0.94 ICMT (0.47) PTGER4CNR2PSEN1PSEN2APH1B
SCHEMBL28573755 0.90 APP (0.47) PTGER4CNR2PSEN1PSEN2APH1B
SCHEMBL29677507 0.90 APP (0.47) PTGER4CNR2PSEN1PSEN2APH1B
SCHEMBL28567473 0.87 PTGER4 (0.54) PTGER4MAPTSMN1; SMN2TDP1KDM4E
SCHEMBL29677645 0.87 PTGER4 (0.54) PTGER4MAPTSMN1; SMN2TDP1KDM4E
SCHEMBL29677329 0.83 PTGER4 (0.58) PTGER4MAPTSMN1; SMN2TDP1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112898799-B Carbazole organic dye and preparation method thereof, dye-sensitized titanium dioxide composite catalyst and preparation method and application thereof 江苏大学 2022-07-15 CN disclosed