Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 10/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | CDC25B | P30305 | 1/20 | 0.37 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28914590 | 0.85 | SLC22A12 (0.46) | SLC22A12PDK2CDC25BPDK4CYP1A2 | |
| SCHEMBL21049181 | 0.78 | SLC22A12 (0.42) | SLC22A12PDK2KDM4ECYP1A2CYP2C19 | |
| SCHEMBL21049177 | 0.77 | SLC22A12 (0.40) | SLC22A12PDK2KDM4ECDC25BCYP1A2 | |
| SCHEMBL30063598 | 0.77 | SLC22A12 (0.40) | SLC22A12PDK2KDM4ECDC25BCYP1A2 | |
| SCHEMBL30881827 | 0.72 | F12 (0.44) | SLC22A12PDK2KDM4EBACE1PDK4 | |
| SCHEMBL21917156 | 0.72 | F12 (0.44) | SLC22A12PDK2KDM4EBACE1PDK4 | |
| SCHEMBL21049187 | 0.72 | MEN1 (0.52) | SLC22A12MEN1MAPTKMT2A | |
| SCHEMBL28899767 | 0.70 | SLC22A12 (0.57) | SLC22A12PDK2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL30104164 | 0.70 | SLC22A12 (0.57) | SLC22A12PDK2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL28806716 | 0.70 | IDO1 (0.52) | SLC22A12PDK2PDK4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114685485-A | Synthesis method of pyridylimidazole thiopropionic acid anti-gout compound | 山东海雅医药科技有限公司 | 2022-07-01 | — | — | CN | claimed |
| CN-114685485-A | Synthesis method of pyridylimidazole thiopropionic acid anti-gout compound | 山东海雅医药科技有限公司 | 2022-07-01 | — | — | CN | disclosed |