Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 10/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CDC25B | P30305 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21049177 | 1.00 | SLC22A12 (0.40) | SLC22A12ALDH1A1MAPTPDK2EGFR | |
| SCHEMBL21049172 | 0.79 | ALDH1A1 (0.55) | SLC22A12ALDH1A1MAPTEGFRHTT | |
| SCHEMBL29678020 | 0.77 | SLC22A12 (0.46) | SLC22A12MAPTPDK2KDM4ECYP2C9 | |
| SCHEMBL28914590 | 0.76 | SLC22A12 (0.46) | SLC22A12PDK2EGFRCYP2C9CYP1A2 | |
| SCHEMBL31178670 | 0.71 | AXL (0.53) | SLC22A12PDK2KDM4EPOLBHTT | |
| SCHEMBL28806716 | 0.69 | IDO1 (0.52) | SLC22A12PDK2 | |
| SCHEMBL29517316 | 0.69 | AOC1 (0.42) | ALDH1A1MAPTKDM4E | |
| SCHEMBL793757 | 0.69 | AOC1 (0.42) | ALDH1A1MAPTKDM4E | |
| SCHEMBL247570 | 0.69 | ALDH1A1 (0.50) | ALDH1A1MAPTPDK2KDM4ECYP3A4 | |
| SCHEMBL31178978 | 0.68 | AXL (0.49) | ALDH1A1PDK2KDM4EPOLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115322190-B | Pyridoimidazole acyl sulfonamide derivative, and preparation method and application thereof | 山东大学 | 2023-09-22 | — | — | CN | disclosed |
| CN-115322190-A | Pyridoimidazole acylsulfonamide derivative and preparation method and application thereof | 山东大学 | 2022-11-11 | — | — | CN | disclosed |