SCHEMBL29678217

SCHEMBL29678217

CC(C)c1c(-c2cnn(C(C)(C)C)c2)nc2c(C#N)c[nH]n2c1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ KDM5A P29375 19/20 1.00
▸ KDM5B Q9UGL1 4/20 1.00
▸ KDM5C P41229 2/20 1.00
▸ KDM4C Q9H3R0 2/20 1.00
▸ KDM6B O15054 1/20 0.66
▸ KDM5D Q9BY66 1/20 0.66
▸ PHF8 Q9UPP1 1/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29549478 0.79 KDM5A (1.00) KDM5AKDM5BKDM5CKDM4CKDM6B
Hydrochloric Acid SCHEMBL31236648 0.78 KDM5A (0.98) KDM5AKDM5BKDM5CKDM4CKDM6B
SCHEMBL17547804 0.71 KDM5A (0.55) KDM5AKDM5BKDM5CKDM4C
SCHEMBL17547867 0.63 KDM5A (0.46) KDM5AKDM5BKDM5CKDM4C
SCHEMBL16050360 0.63 KDM5A (0.46) KDM5AKDM5BKDM5CKDM4CKDM6B
SCHEMBL17547865 0.62 KDM5B (0.50) KDM5AKDM5BKDM5CKDM4C
SCHEMBL16050579 0.62 KDM5A (0.45) KDM5AKDM5BKDM5CKDM4C
SCHEMBL30332210 0.62 PDK2 (0.48) KDM5AKDM5BKDM5CKDM4C
SCHEMBL17547819 0.62 KDM5A (0.45) KDM5AKDM5BKDM5CKDM4C
SCHEMBL16092351 0.62 KDM5B (0.49) KDM5AKDM5BKDM5CKDM4C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120137885-A Culture solution additive for improving embryo development potential and application thereof 山东大学 2025-06-13 — — CN claimed
WO-2024233765-A1 THERAPEUTIC APPROACH TO BLOCK TERMINAL EXHAUSTION OF T CELLS AND SYNERGIZE THE EFFICACY OF T CELL IMMUNOTHERAPIES OHIO STATE INNOVATION FOUNDATION (US) 2024-11-14 — — WO claimed
CN-120137885-A Culture solution additive for improving embryo development potential and application thereof 山东大学 2025-06-13 — — CN disclosed
WO-2024233765-A1 THERAPEUTIC APPROACH TO BLOCK TERMINAL EXHAUSTION OF T CELLS AND SYNERGIZE THE EFFICACY OF T CELL IMMUNOTHERAPIES OHIO STATE INNOVATION FOUNDATION (US) 2024-11-14 — — WO disclosed
US-20220192984-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING OTIC THERAPEUTIC AGENTS AND RELATED METHODS Frequency Therapeutics, Inc. 2022-06-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220192984-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING OTIC THERAPEUTIC AGENTS AND RELATED METHODS OTC, EXOSC5, ENTPD5 KDM5A 4642/4885KDM5B 4560/4885KDM5C 4362/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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