Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 19/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | SLC2A9 | Q9NRM0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21049171 | 1.00 | SLC22A12 (0.60) | SLC22A12CYP2C9CYP2C19CYP3A4CYP1A2 | |
| SCHEMBL25955290 | 0.81 | SLC22A12 (0.72) | SLC22A12CYP2C9CYP2C19CYP3A4CYP1A2 | |
| SCHEMBL21049189 | 0.81 | SLC22A12 (0.45) | SLC22A12CYP2C9CYP2C19CYP3A4CYP1A2 | |
| SCHEMBL25955294 | 0.80 | SLC22A12 (0.79) | SLC22A12CYP2C9CYP2C19CYP3A4CYP1A2 | |
| SCHEMBL19851018 | 0.80 | SLC22A12 (0.67) | SLC22A12CYP2C9CYP2C19CYP3A4CYP1A2 | |
| SCHEMBL19851105 | 0.80 | SLC22A12 (0.67) | SLC22A12CYP2C9CYP2C19CYP3A4CYP1A2 | |
| SCHEMBL19851009 | 0.80 | SLC22A12 (0.79) | SLC22A12CYP2C9CYP2C19CYP3A4CYP1A2 | |
| SCHEMBL19851015 | 0.77 | SLC22A12 (0.66) | SLC22A12CYP2C9CYP2C19CYP3A4CYP1A2 | |
| SCHEMBL25955010 | 0.77 | SLC22A12 (0.82) | SLC22A12CYP2C9CYP2C19CYP3A4CYP1A2 | |
| SCHEMBL31268399 | 0.77 | SLC22A12 (0.64) | SLC22A12CYP2C9CYP2C19CYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114685485-B | Synthesis method of pyridoimidazole thiopropionic acid anti-gout compound | 山东海雅医药科技有限公司 | 2024-03-26 | — | — | CN | disclosed |
| CN-115385907-B | Room-temperature stable crystal form of pyridoimidazole thiopropionic acid anti-gout compound and preparation method thereof | 山东海雅医药科技有限公司 | 2024-01-16 | — | — | CN | disclosed |
| CN-115322190-B | Pyridoimidazole acyl sulfonamide derivative, and preparation method and application thereof | 山东大学 | 2023-09-22 | — | — | CN | disclosed |
| CN-115385907-A | Stable crystal form of pyridino-imidazole thiopropionic acid anti-gout compound at room temperature and preparation method thereof | 山东海雅医药科技有限公司 | 2022-11-25 | — | — | CN | disclosed |
| CN-115322190-A | Pyridoimidazole acylsulfonamide derivative and preparation method and application thereof | 山东大学 | 2022-11-11 | — | — | CN | disclosed |
| CN-114685485-A | Synthesis method of pyridylimidazole thiopropionic acid anti-gout compound | 山东海雅医药科技有限公司 | 2022-07-01 | — | — | CN | disclosed |