SCHEMBL29679186

SCHEMBL29679186

CC(C)(C)OC(=O)CC[C@H](NC(=O)N[C@@H](CCCCNC(=O)[C@H](Cc1ccc(-c2ccccc2)cc1)NC(=O)C1CCC(CNC(=O)OCC2c3ccccc3-c3ccccc32)CC1)C(=O)OC(C)(C)C)C(=O)OC(C)(C)C

nearest known ligand 0.49

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ FOLH1 Q04609 6/20 0.45
▸ ATM Q13315 2/20 0.45
▸ KMT2A Q03164 2/20 0.45
▸ MEN1 O00255 1/20 0.44
▸ PLG P00747 4/20 0.43
▸ PRSS1 P07477 4/20 0.43
▸ PRSS2 P07478 4/20 0.43
▸ PRSS3 P35030 4/20 0.43
▸ TLR2 O60603 1/20 0.40
▸ TLR1 Q15399 1/20 0.40
▸ PLAU P00749 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29679144 0.95 FOLH1 (0.44) FOLH1ATMKMT2AMEN1PLG
SCHEMBL29678960 0.95 FOLH1 (0.45) FOLH1ATMKMT2AMEN1PLG
SCHEMBL29679075 0.94 FOLH1 (0.44) FOLH1ATMKMT2AMEN1PLG
SCHEMBL29678849 0.92 FOLH1 (0.54) FOLH1ATMKMT2AMEN1PLG
SCHEMBL29679163 0.92 FOLH1 (0.54) FOLH1ATMKMT2AMEN1PLG
SCHEMBL29335236 0.92 FOLH1 (0.54) FOLH1ATMKMT2AMEN1PLG
SCHEMBL30971343 0.92 FOLH1 (0.54) FOLH1ATMKMT2AMEN1PLG
SCHEMBL29679232 0.92 FOLH1 (0.45) FOLH1ATMKMT2AMEN1PLG
SCHEMBL29679034 0.91 KMT2A (0.43) FOLH1ATMKMT2AMEN1TLR2
SCHEMBL29678956 0.91 FOLH1 (0.43) FOLH1ATMKMT2AMEN1PLG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230072421-A1 TARGETED RADIOPHARMACEUTICALS FOR THE DIAGNOSIS AND TREATMENT OF PROSTATE CANCER BAYER AS (NO) 2023-03-09 — — US disclosed
EP-4003959-A1 TARGETED RADIOPHARMACEUTICALS FOR THE DIAGNOSIS AND TREATMENT OF PROSTATE CANCER Bayer AS (NO) 2022-06-01 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230072421-A1 TARGETED RADIOPHARMACEUTICALS FOR THE DIAGNOSIS AND TREATMENT OF PROSTATE CANCER KLK3, AR, SHBG FOLH1 43/4885ATM 2227/4885KMT2A 2321/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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