Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 11/20 | 0.48 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.38 |
| ▸ | GAK | O14976 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | PRCP | P42785 | 1/20 | 0.35 |
| ▸ | OTUD7B | Q6GQQ9 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29679888 | 0.83 | USP30 (0.62) | USP30PRCP | |
| SCHEMBL20028826 | 0.76 | USP30 (0.57) | USP30 | |
| SCHEMBL29562443 | 0.75 | USP30 (0.54) | USP30CHEK1 | |
| SCHEMBL29563339 | 0.74 | USP30 (0.56) | USP30 | |
| SCHEMBL19385029 | 0.74 | USP30 (0.70) | USP30 | |
| SCHEMBL29679852 | 0.73 | USP30 (0.59) | USP30 | |
| SCHEMBL29679901 | 0.73 | USP30 (0.44) | USP30 | |
| SCHEMBL20028994 | 0.72 | USP30 (0.62) | USP30 | |
| SCHEMBL19385088 | 0.71 | USP30 (0.71) | USP30 | |
| SCHEMBL19385090 | 0.71 | USP30 (0.71) | USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109790148-B | Cyano-substituted heterocycles having USP30 inhibitor activity | 特殊治疗有限公司 | 2022-06-07 | — | — | CN | disclosed |