SCHEMBL29679888

SCHEMBL29679888

N#CN1CCCCC1c1nc2cc(-c3ccccc3)cnc2[nH]1

nearest known ligand 0.62

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ USP30 Q70CQ3 18/20 0.62
▸ PRCP P42785 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29562443 0.87 USP30 (0.54) USP30
SCHEMBL29563339 0.86 USP30 (0.56) USP30
SCHEMBL29679479 0.83 USP30 (0.48) USP30PRCP
SCHEMBL20028994 0.80 USP30 (0.62) USP30
SCHEMBL19385029 0.80 USP30 (0.70) USP30
SCHEMBL29562718 0.79 USP30 (0.83) USP30PRCP
SCHEMBL19400823 0.79 USP30 (0.83) USP30PRCP
SCHEMBL29562373 0.78 USP30 (0.61) USP30
SCHEMBL19385284 0.77 USP30 (1.00) USP30PRCP
SCHEMBL29562247 0.77 USP30 (0.66) USP30

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109790148-B Cyano-substituted heterocycles having USP30 inhibitor activity 特殊治疗有限公司 2022-06-07 — — CN disclosed
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