Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAT2A | P31153 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.31 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.31 |
| ▸ | SRC | P12931 | 2/20 | 0.31 |
| ▸ | CCR6 | P51684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24528694 | 1.00 | KDM4E (0.38) | KDM4EALDH1A1LMNAMAT2AATM | |
| SCHEMBL24528583 | 0.84 | KDM4E (0.38) | KDM4EALDH1A1LMNAATMMEN1 | |
| SCHEMBL29680660 | 0.84 | KDM4E (0.38) | KDM4EALDH1A1LMNAATMMEN1 | |
| SCHEMBL29680746 | 0.81 | KDM4E (0.37) | KDM4EALDH1A1LMNAATMMEN1 | |
| SCHEMBL24528512 | 0.81 | KDM4E (0.37) | KDM4EALDH1A1LMNAATMMEN1 | |
| SCHEMBL24528715 | 0.80 | KDM4E (0.38) | KDM4EALDH1A1LMNAATMMEN1 | |
| SCHEMBL29680698 | 0.80 | KDM4E (0.38) | KDM4EALDH1A1LMNAATMMEN1 | |
| SCHEMBL24528636 | 0.80 | NUDT1 (0.41) | KDM4EALDH1A1LMNAATMMEN1 | |
| SCHEMBL29680600 | 0.79 | TMEM97 (0.43) | KDM4EMEN1KMT2AMAPTMAPK1 | |
| SCHEMBL24528695 | 0.79 | KDM4E (0.34) | KDM4EALDH1A1LMNAATMMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4263539-A1 | 6-6 OR 5-6 FUSED BICYCLIC COMPOUNDS COMPRISING A PYRI(MI)DINE RING USEFUL IN THE TREATMENT OF INFECTIOUS DISEASES | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - INSERM (FR) | 2023-10-25 | — | — | EP | disclosed |
| WO-2022129376-A1 | 6-6 OR 5-6 FUSED BICYCLIC COMPOUNDS COMPRISING A PYRI(MI)DINE RING USEFUL IN THE|TREATMENT OF INFECTIOUS DISEASES | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2022-06-23 | — | — | WO | disclosed |