Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21907256 | 1.00 | RET (0.33) | RET | |
| SCHEMBL21801387 | 0.79 | RET (0.34) | RET | |
| SCHEMBL21801354 | 0.79 | RET (0.39) | RET | |
| SCHEMBL29182339 | 0.78 | RET (0.35) | RET | |
| SCHEMBL21801443 | 0.77 | RET (0.33) | RET | |
| SCHEMBL21908104 | 0.77 | RET (0.43) | RET | |
| SCHEMBL21801822 | 0.76 | RET (0.36) | RET | |
| SCHEMBL21801379 | 0.76 | RET (0.34) | RET | |
| SCHEMBL21801346 | 0.76 | NR1H4 (0.31) | RET | |
| SCHEMBL21801510 | 0.76 | RET (0.41) | RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3849986-B1 | FUSED HETEROCYCLIC COMPOUNDS AS RET KINASE INHIBITORS | ARRAY BIOPHARMA INC (US) | 2022-06-08 | — | — | EP | disclosed |