Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 16/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 16/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 15/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28747557 | 1.00 | HTR2A (0.57) | HTR2ASLC6A4KCNH2SLC6A2SLC6A3 | |
| SCHEMBL1341069 | 0.81 | GAA (0.62) | HTR2ASLC6A4KCNH2SLC6A2SLC6A3 | |
| SCHEMBL21186228 | 0.77 | NR4A1 (0.50) | GAARCE1CYP2C19KDM4EMEN1 | |
| SCHEMBL5836497 | 0.76 | HTR2A (0.68) | HTR2ASLC6A4KCNH2SLC6A2SLC6A3 | |
| SCHEMBL2812244 | 0.76 | MAOB (0.47) | HTR2ASLC6A4KCNH2GAACYP2C19 | |
| SCHEMBL2551468 | 0.76 | MAPT (0.56) | HTR2ASLC6A4KCNH2CYP2C19KDM4E | |
| SCHEMBL11018978 | 0.75 | ALDH1A1 (0.50) | HTR2ASLC6A4KCNH2SLC6A2SLC6A3 | |
| SCHEMBL31522170 | 0.75 | SLC6A4 (0.45) | HTR2ASLC6A4KCNH2SLC6A2SLC6A3 | |
| SCHEMBL21186204 | 0.75 | ALDH1A1 (0.51) | HTR2ASLC6A4KCNH2SLC6A2SLC6A3 | |
| SCHEMBL5314078 | 0.74 | HTR2A (0.71) | HTR2ASLC6A4KCNH2SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114560826-B | Thiazole amide compound containing diphenyl ether group and preparation method and application thereof | 安徽理工大学 | 2024-06-25 | — | — | CN | disclosed |
| CN-114560826-A | Diphenyl ether group-containing thiazole amide compound and preparation method and application thereof | 安徽理工大学 | 2022-05-31 | — | — | CN | disclosed |