Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 9/20 | 0.51 |
| ▸ | CCKBR | P32239 | 7/20 | 0.51 |
| ▸ | CCKAR | P32238 | 6/20 | 0.51 |
| ▸ | GLP1R | P43220 | 3/20 | 0.47 |
| ▸ | TFPI | P10646 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29728184 | 0.95 | TFPI (0.50) | OPRD1CCKBRCCKARGLP1RTFPI | |
| SCHEMBL31069954 | 0.87 | OPRD1 (0.51) | OPRD1CCKBRCCKARGLP1R | |
| SCHEMBL30668514 | 0.87 | OPRD1 (0.53) | OPRD1CCKBRCCKAR | |
| SCHEMBL30350802 | 0.86 | OPRD1 (0.53) | OPRD1CCKBRCCKAR | |
| SCHEMBL29555813 | 0.84 | ACE (0.53) | — | |
| SCHEMBL30512633 | 0.84 | F2 (0.49) | OPRD1GLP1R | |
| SCHEMBL29635274 | 0.83 | TFPI (0.55) | TFPI | |
| SCHEMBL31181956 | 0.83 | OPRD1 (0.51) | OPRD1 | |
| SCHEMBL30974519 | 0.83 | ACE (0.55) | OPRD1 | |
| SCHEMBL29679934 | 0.82 | F2 (0.52) | OPRD1CCKBRCCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114874292-A | Multi-target chimeric peptide compound, preparation method and application thereof | 南通大学 | 2022-08-09 | — | — | CN | claimed |
| CN-113072620-B | PD-1 targeting peptide with analgesic activity, and synthesis method and application thereof | 南通大学 | 2022-07-05 | — | — | CN | claimed |
| CN-118878633-A | Application of multi-target peptide in preparing analgesic drug | 南通大学 | 2024-11-01 | — | — | CN | disclosed |
| CN-118684732-A | Method for preparing AT-01 by liquid phase fragment condensation | 南通大学 | 2024-09-24 | — | — | CN | disclosed |
| CN-114874292-A | Multi-target chimeric peptide compound, preparation method and application thereof | 南通大学 | 2022-08-09 | — | — | CN | disclosed |
| CN-113072620-B | PD-1 targeting peptide with analgesic activity, and synthesis method and application thereof | 南通大学 | 2022-07-05 | — | — | CN | disclosed |