Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 15/20 | 0.72 |
| ▸ | HTT | P42858 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28771961 | 1.00 | NR3C1 (0.72) | NR3C1HTTMAPTPOLBPDE4B | |
| SCHEMBL28772156 | 0.85 | NR3C1 (1.00) | NR3C1 | |
| SCHEMBL29683571 | 0.81 | HTT (0.74) | NR3C1HTT | |
| SCHEMBL28771879 | 0.81 | HTT (0.74) | NR3C1HTT | |
| SCHEMBL12476846 | 0.75 | CA12 (0.52) | NR3C1HTTMAPTPOLBPDE4B | |
| SCHEMBL13317270 | 0.73 | HTT (0.61) | NR3C1HTT | |
| SCHEMBL3620178 | 0.73 | HTT (0.61) | NR3C1HTT | |
| SCHEMBL28771908 | 0.72 | NR3C1 (0.84) | NR3C1HTT | |
| SCHEMBL28771855 | 0.72 | NR3C1 (0.84) | NR3C1HTT | |
| SCHEMBL29684069 | 0.72 | NR3C1 (0.84) | NR3C1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114699412-A | Sulfonamide compound and application thereof in preparation of medicine for treating autoimmune diseases | 浙江大学 | 2022-07-05 | — | — | CN | disclosed |