Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 8/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29684278 | 0.99 | IRAK4 (0.46) | IRAK4TP53MAPK1L3MBTL1KMT2A | |
| SCHEMBL29684509 | 0.96 | TP53 (0.47) | IRAK4TP53MAPK1L3MBTL1KMT2A | |
| SCHEMBL29684653 | 0.92 | POLB (0.48) | IRAK4KMT2AMEN1GAAKDM4E | |
| SCHEMBL29684433 | 0.91 | IRAK4 (0.44) | IRAK4KMT2AMEN1GAAKDM4E | |
| SCHEMBL29684155 | 0.89 | IRAK4 (0.43) | IRAK4KMT2AMEN1GAAKDM4E | |
| SCHEMBL29683974 | 0.83 | IRAK4 (0.51) | IRAK4KMT2AMEN1KDM4EHTT | |
| SCHEMBL29684141 | 0.81 | KMT2A (0.47) | IRAK4L3MBTL1KMT2AMEN1GAA | |
| SCHEMBL29684244 | 0.80 | IRAK4 (0.50) | IRAK4KMT2AMEN1KDM4EHTT | |
| SCHEMBL28844977 | 0.80 | KMT2A (0.53) | IRAK4KMT2AMEN1KDM4EHTT | |
| SCHEMBL31611989 | 0.80 | IRAK4 (0.41) | IRAK4KMT2AMEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114763346-A | Compound for inducing chondrogenesis and application thereof | 华东师范大学 | 2022-07-19 | — | — | CN | claimed |
| CN-114763346-A | Compound for inducing chondrogenesis and application thereof | 华东师范大学 | 2022-07-19 | — | — | CN | disclosed |