Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.53 |
| ▸ | MEN1 | O00255 | 6/20 | 0.53 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29683974 | 0.87 | IRAK4 (0.51) | KMT2AMEN1IRAK4MAPTKDM4E | |
| SCHEMBL29684244 | 0.86 | IRAK4 (0.50) | KMT2AMEN1IRAK4MAPTKDM4E | |
| SCHEMBL29684162 | 0.84 | IRAK4 (0.50) | KMT2AMEN1IRAK4NPSR1MAPT | |
| SCHEMBL29684640 | 0.84 | IRAK4 (0.48) | KMT2AMEN1IRAK4MAPTKDM4E | |
| SCHEMBL29684653 | 0.84 | POLB (0.48) | KMT2AMEN1IRAK4MAPTKDM4E | |
| SCHEMBL28844941 | 0.83 | KCNMA1 (0.60) | KMT2AMEN1IRAK4NPSR1MAPT | |
| SCHEMBL29732897 | 0.83 | KCNMA1 (0.60) | KMT2AMEN1IRAK4NPSR1MAPT | |
| SCHEMBL29684331 | 0.83 | HSP90AA1 (0.53) | KMT2AMEN1IRAK4MAPTPOLB | |
| SCHEMBL29684141 | 0.83 | KMT2A (0.47) | KMT2AMEN1IRAK4MAPTKDM4E | |
| SCHEMBL29684320 | 0.83 | IRAK4 (0.47) | KMT2AMEN1IRAK4MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114763347-B | Compound for inducing mesenchymal stem cells to differentiate into cartilage and application thereof | 华东师范大学 | 2024-06-21 | — | — | CN | claimed |
| CN-114763347-A | Compound for inducing mesenchymal stem cells to differentiate towards cartilage and application thereof | 华东师范大学 | 2022-07-19 | — | — | CN | claimed |
| CN-114763347-B | Compound for inducing mesenchymal stem cells to differentiate into cartilage and application thereof | 华东师范大学 | 2024-06-21 | — | — | CN | disclosed |
| CN-114763347-A | Compound for inducing mesenchymal stem cells to differentiate towards cartilage and application thereof | 华东师范大学 | 2022-07-19 | — | — | CN | disclosed |