Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK6 | Q00534 | 15/20 | 0.59 |
| ▸ | CCND1 | P24385 | 15/20 | 0.59 |
| ▸ | CDK4 | P11802 | 8/20 | 0.58 |
| ▸ | CCNA2 | P20248 | 6/20 | 0.55 |
| ▸ | CDK2 | P24941 | 6/20 | 0.55 |
| ▸ | CCND3 | P30281 | 6/20 | 0.55 |
| ▸ | CDK1 | P06493 | 5/20 | 0.55 |
| ▸ | CCNE2 | O96020 | 4/20 | 0.55 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.54 |
| ▸ | CDK7 | P50613 | 1/20 | 0.53 |
| ▸ | CCNH | P51946 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24483256 | 1.00 | CDK6 (0.59) | CDK6CCND1CDK4CCNA2CDK2 | |
| Hydrochloric Acid SCHEMBL29684440 | 0.99 | CDK6 (0.58) | CDK6CCND1CDK4CCNA2CDK2 | |
| SCHEMBL29684328 | 0.88 | CDK6 (0.70) | CDK6CCND1CDK4CCNA2CCND3 | |
| SCHEMBL24483255 | 0.88 | CDK6 (0.70) | CDK6CCND1CDK4CCNA2CCND3 | |
| SCHEMBL24483430 | 0.88 | CDK6 (0.64) | CDK6CCND1CDK4CCNA2CDK2 | |
| Hydrochloric Acid SCHEMBL29684067 | 0.87 | CDK6 (0.69) | CDK6CCND1CDK4CCNA2CCND3 | |
| SCHEMBL24483262 | 0.87 | CDK6 (0.69) | CDK6CCND1CDK4CCNA2CDK2 | |
| SCHEMBL29683983 | 0.87 | CDK6 (0.69) | CDK6CCND1CDK4CCNA2CDK2 | |
| Hydrochloric Acid SCHEMBL29684277 | 0.86 | CDK6 (0.68) | CDK6CCND1CDK4CCNA2CDK2 | |
| SCHEMBL24483435 | 0.83 | CDK6 (0.66) | CDK6CCND1CDK4CCNA2CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022113003-A1 | CDK INHIBITORS | RHIZEN PHARMACEUTICALS AG (CH) | 2022-06-02 | — | — | WO | claimed |
| WO-2022113003-A1 | CDK INHIBITORS | RHIZEN PHARMACEUTICALS AG (CH) | 2022-06-02 | — | — | WO | disclosed |