Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK6 | Q00534 | 16/20 | 0.70 |
| ▸ | CCND1 | P24385 | 14/20 | 0.70 |
| ▸ | DYRK2 | Q92630 | 2/20 | 0.62 |
| ▸ | CDK4 | P11802 | 6/20 | 0.60 |
| ▸ | CCND3 | P30281 | 3/20 | 0.60 |
| ▸ | CDK1 | P06493 | 1/20 | 0.58 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24483255 | 1.00 | CDK6 (0.70) | CDK6CCND1DYRK2CDK4CCND3 | |
| Hydrochloric Acid SCHEMBL29684067 | 0.99 | CDK6 (0.69) | CDK6CCND1DYRK2CDK4CCND3 | |
| SCHEMBL29684177 | 0.88 | CDK6 (0.75) | CDK6CCND1DYRK2CDK4CCND3 | |
| SCHEMBL24482653 | 0.88 | CDK6 (0.75) | CDK6CCND1DYRK2CDK4CCND3 | |
| SCHEMBL24483256 | 0.88 | CDK6 (0.59) | CDK6CCND1CDK4CCND3CDK1 | |
| SCHEMBL29684221 | 0.88 | CDK6 (0.59) | CDK6CCND1CDK4CCND3CDK1 | |
| Hydrochloric Acid SCHEMBL29684440 | 0.87 | CDK6 (0.58) | CDK6CCND1CDK4CCND3CDK1 | |
| Hydrochloric Acid SCHEMBL29684319 | 0.87 | CDK6 (0.74) | CDK6CCND1DYRK2CDK4CCND3 | |
| SCHEMBL24482650 | 0.83 | CDK6 (0.69) | CDK6CCND1DYRK2CDK4CCND3 | |
| SCHEMBL29684497 | 0.83 | CDK6 (0.69) | CDK6CCND1DYRK2CDK4CCND3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022113003-A1 | CDK INHIBITORS | RHIZEN PHARMACEUTICALS AG (CH) | 2022-06-02 | — | — | WO | claimed |
| WO-2022113003-A1 | CDK INHIBITORS | RHIZEN PHARMACEUTICALS AG (CH) | 2022-06-02 | — | — | WO | disclosed |