Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.53 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.53 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CCR1 | P32246 | 1/20 | 0.41 |
| ▸ | CCR8 | P51685 | 1/20 | 0.41 |
| ▸ | GBA1 | P04062 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL869497 | 1.00 | KMT2A (0.53) | KMT2AMEN1OPRM1OPRD1P2RX7 | |
| Trifluoroacetic Acid SCHEMBL868947 | 0.90 | KMT2A (0.49) | KMT2AMEN1OPRM1OPRD1P2RX7 | |
| SCHEMBL4495296 | 0.85 | AKR1B1 (0.48) | GAAMAPTSMN1; SMN2KDM4ETDP1 | |
| SCHEMBL28631700 | 0.85 | KMT2A (0.47) | KMT2AMEN1OPRM1OPRD1P2RX7 | |
| SCHEMBL6900384 | 0.84 | P2RX7 (0.46) | KMT2AMEN1OPRM1OPRD1P2RX7 | |
| SCHEMBL29351319 | 0.82 | P2RX7 (0.49) | KMT2AMEN1OPRM1OPRD1P2RX7 | |
| SCHEMBL6510299 | 0.82 | P2RX7 (0.49) | KMT2AMEN1OPRM1OPRD1P2RX7 | |
| SCHEMBL14592085 | 0.82 | MEN1 (0.48) | KMT2AMEN1OPRM1OPRD1RAB9A | |
| Propionic Acid SCHEMBL28532699 | 0.81 | MEN1 (0.47) | KMT2AMEN1OPRM1OPRD1P2RX7 | |
| SCHEMBL17743752 | 0.81 | FFAR1 (0.52) | KMT2AMEN1OPRM1OPRD1P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072539-A1 | AMINO ACID COMPOUNDS WITH NITROGEN LINKERS AND USES THEREOF | PLIANT THERAPEUTICS, INC. (US) | 2025-04-03 | — | — | WO | disclosed |
| US-20230348369-A1 | NAMPT MODULATORS | CYTOKINETICS, INC. | 2023-11-02 | — | — | US | disclosed |
| CN-116023375-A | Heterocyclic derivative, preparation method and application thereof | 成都苑东生物制药股份有限公司 | 2023-04-28 | — | — | CN | disclosed |
| CN-112279852-B | Triazolo-pyrimidine compounds and uses thereof | 迪哲(江苏)医药股份有限公司 | 2023-01-17 | — | — | CN | disclosed |
| CN-114805346-A | Heterocyclic derivative, preparation method and application thereof | 成都硕德药业有限公司 | 2022-07-29 | — | — | CN | disclosed |
| CN-111635408-B | Triazolo-pyrimidine compounds and uses thereof | 迪哲(江苏)医药股份有限公司 | 2022-07-22 | — | — | CN | disclosed |
| CN-114710956-A | PERK-INHIBITING PYRROLOPYRIMIDINE COMPOUNDS | 希伯塞尔股份有限公司 | 2022-07-05 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230348369-A1 | NAMPT MODULATORS | NAMPT, NNT, NAPRT | KMT2A 1973/4885MEN1 110/4885OPRM1 1236/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.