Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 6/20 | 0.69 |
| ▸ | TNFRSF1A | P19438 | 6/20 | 0.67 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | BCHE | P06276 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | RELA | Q04206 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4620101 | 0.83 | ABCG2 (0.74) | ABCG2TNFRSF1AABCB1LMNAMAPT | |
| SCHEMBL4620096 | 0.83 | ABCG2 (0.74) | ABCG2TNFRSF1AABCB1LMNAMAPT | |
| SCHEMBL25302141 | 0.83 | ABCG2 (0.74) | ABCG2TNFRSF1AABCB1LMNAMAPT | |
| SCHEMBL30428796 | 0.83 | ABCG2 (0.74) | ABCG2TNFRSF1AABCB1LMNAMAPT | |
| SCHEMBL10583111 | 0.82 | TNFRSF1A (0.84) | ABCG2TNFRSF1AABCB1LMNAMAPT | |
| SCHEMBL14325695 | 0.82 | ABCG2 (0.72) | ABCG2TNFRSF1AABCB1LMNAMAPT | |
| SCHEMBL10583102 | 0.82 | TNFRSF1A (0.84) | ABCG2TNFRSF1AABCB1LMNAMAPT | |
| 3',4'-Dimethoxychalcone SCHEMBL12485318 | 0.81 | TNFRSF1A (1.00) | ABCG2TNFRSF1AABCB1LMNAMAPT | |
| 3',4'-Dimethoxychalcone SCHEMBL12485314 | 0.81 | TNFRSF1A (1.00) | ABCG2TNFRSF1AABCB1LMNAMAPT | |
| SCHEMBL11658599 | 0.80 | ABCG2 (0.73) | ABCG2TNFRSF1AABCB1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11857657-B2 | Diarylalkanes as potent inhibitors of binuclear enzymes | UNIGEN, INC. (US) | 2024-01-02 | — | — | US | disclosed |
| CN-109134205-B | Diarylalkanes as potent inhibitors of binuclear enzymes | 尤尼根公司 | 2022-07-19 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11857657-B2 | Diarylalkanes as potent inhibitors of binuclear enzymes | TYR, DDT, HAAO | ABCG2 1756/4885TNFRSF1A 3525/4885ABCB1 341/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.