Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 6/20 | 0.74 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.70 |
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.68 |
| ▸ | MAOB | P27338 | 2/20 | 0.61 |
| ▸ | MAOA | P21397 | 1/20 | 0.61 |
| ▸ | SNCA | P37840 | 1/20 | 0.60 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.60 |
| ▸ | PDE4A | P27815 | 1/20 | 0.60 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.60 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.60 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | ATM | Q13315 | 2/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30428796 | 1.00 | ABCG2 (0.74) | ABCG2ABCB1TNFRSF1AMAOBMAOA | |
| SCHEMBL4620101 | 1.00 | ABCG2 (0.74) | ABCG2ABCB1TNFRSF1AMAOBMAOA | |
| SCHEMBL5599401 | 0.92 | DPP4 (0.67) | ABCG2ABCB1TNFRSF1AMAOBMAOA | |
| SCHEMBL25302141 | 0.86 | ABCG2 (0.74) | ABCG2ABCB1TNFRSF1AMAOBNR1H4 | |
| SCHEMBL5599587 | 0.86 | PTPN1 (0.57) | ABCG2ABCB1TNFRSF1AMAOBMAOA | |
| SCHEMBL14325695 | 0.85 | ABCG2 (0.72) | ABCG2ABCB1TNFRSF1AMAOBMAPT | |
| SCHEMBL2971618 | 0.85 | CHRNA7 (0.67) | ABCG2ABCB1TNFRSF1ASNCATDP1 | |
| SCHEMBL2971621 | 0.85 | CHRNA7 (0.67) | ABCG2ABCB1TNFRSF1ASNCATDP1 | |
| SCHEMBL3740584 | 0.84 | ABCG2 (0.62) | ABCG2ABCB1TNFRSF1ASNCAPDE4A | |
| SCHEMBL29684615 | 0.83 | ABCG2 (0.69) | ABCG2ABCB1TNFRSF1AMAPTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116162079-A | Synthesis method of aminocoumarin compound | 浙江工业大学 | 2023-05-26 | — | — | CN | disclosed |
| EP-1888174-A1 | USE OF CHALCONES FOR THE TREATMENT OF VIRAL DISORDERS | Johnson and Johnson Consumer Companies, Inc. (US) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006127539-A1 | USE OF CHALCONES FOR THE TREATMENT OF VIRAL DISORDERS | JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) | 2006-11-30 | — | — | WO | disclosed |
| EP-0428398-A2 | Radiation-sensitive resin composition | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1991-05-22 | — | — | EP | disclosed |