SCHEMBL29685124

SCHEMBL29685124

CCC(N(NC(=O)c1ccc2c(c1C)OCCO2)C(=O)c1cc(C)cc(C)c1)C(C)(C)C

nearest known ligand 0.51

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ABCB1 P08183 4/20 0.38
SMN1; SMN2 Q16637 2/20 0.36
CYP3A4 P08684 1/20 0.36
ALDH1A1 P00352 2/20 0.35
NPC1 O15118 2/20 0.35
RAB9A P51151 2/20 0.35
HPGD P15428 1/20 0.35
MAPT P10636 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL668095 1.00 ABCB1 (0.38) ABCB1SMN1; SMN2CYP3A4ALDH1A1NPC1
SCHEMBL668634 0.94 ABCB1 (0.36) ABCB1SMN1; SMN2CYP3A4ALDH1A1NPC1
SCHEMBL29684859 0.94 ABCB1 (0.36) ABCB1SMN1; SMN2CYP3A4ALDH1A1NPC1
SCHEMBL2683648 0.94 ABCB1 (0.36) ABCB1SMN1; SMN2CYP3A4ALDH1A1NPC1
SCHEMBL18091873 0.92 NPC1 (0.39) ABCB1SMN1; SMN2CYP3A4ALDH1A1NPC1
SCHEMBL29684694 0.91 ABCB1 (0.39) ABCB1SMN1; SMN2CYP3A4ALDH1A1NPC1
SCHEMBL667409 0.91 ABCB1 (0.39) ABCB1SMN1; SMN2CYP3A4ALDH1A1NPC1
SCHEMBL29684822 0.89 PLK1 (0.39) ABCB1SMN1; SMN2ALDH1A1NPC1RAB9A
SCHEMBL667456 0.89 PLK1 (0.39) ABCB1SMN1; SMN2ALDH1A1NPC1RAB9A
SCHEMBL7479127 0.88 ABCB1 (0.39) ABCB1ALDH1A1NPC1RAB9AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118406655-A Modulation of expression of polypeptides by novel gene switch expression systems 普瑞赛格恩公司 2024-07-30 CN disclosed
CN-118159653-A Chimeric receptor therapies 普雷西根公司 2024-06-07 CN disclosed
EP-4274898-A2 CHIMERIC RECEPTOR THERAPY Precigen, Inc. (US) 2023-11-15 EP disclosed
EP-4251278-A1 HUMAN PAPILLOMA VIRUS VACCINES AND USES OF THE SAME FOR HPV ASSOCIATED DISEASES Precigen, Inc. (US) 2023-10-04 EP disclosed
WO-2022150732-A2 CHIMERIC RECEPTOR THERAPY PRECIGEN, INC. (US) 2022-07-14 WO disclosed
WO-2022115470-A1 HUMAN PAPILLOMA VIRUS VACCINES AND USES OF THE SAME FOR HPV ASSOCIATED DISEASES PRECIGEN, INC. (US) 2022-06-02 WO disclosed