SCHEMBL29684694

SCHEMBL29684694

CCc1c(C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(CC)C(C)(C)C)ccc2c1OCCO2

nearest known ligand 0.56

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ABCB1 P08183 3/20 0.39
CYP3A4 P08684 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.36
ALDH1A1 P00352 1/20 0.36
HPGD P15428 1/20 0.36
USP2 O75604 1/20 0.35
MAPT P10636 1/20 0.35
ALOX15 P16050 1/20 0.35
MAPK1 P28482 1/20 0.35
HSD17B10 Q99714 1/20 0.35
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL667409 1.00 ABCB1 (0.39) ABCB1CYP3A4SMN1; SMN2ALDH1A1HPGD
SCHEMBL668085 0.94 ABCB1 (0.38) ABCB1CYP3A4SMN1; SMN2ALDH1A1HPGD
SCHEMBL29786240 0.94 ABCB1 (0.38) ABCB1CYP3A4SMN1; SMN2ALDH1A1HPGD
SCHEMBL29684755 0.94 ABCB1 (0.38) ABCB1CYP3A4SMN1; SMN2ALDH1A1HPGD
SCHEMBL2684734 0.94 ABCB1 (0.38) ABCB1CYP3A4SMN1; SMN2ALDH1A1HPGD
SCHEMBL12841128 0.91 ABCB1 (0.36) ABCB1CYP3A4SMN1; SMN2ALDH1A1HPGD
SCHEMBL17416635 0.91 ABCB1 (0.39) ABCB1CYP3A4SMN1; SMN2ALDH1A1HPGD
SCHEMBL29685124 0.91 ABCB1 (0.38) ABCB1CYP3A4SMN1; SMN2ALDH1A1HPGD
SCHEMBL668095 0.91 ABCB1 (0.38) ABCB1CYP3A4SMN1; SMN2ALDH1A1HPGD
SCHEMBL667482 0.89 PLK1 (0.37) ABCB1SMN1; SMN2ALDH1A1MAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118406655-A Modulation of expression of polypeptides by novel gene switch expression systems 普瑞赛格恩公司 2024-07-30 CN disclosed
CN-118159653-A Chimeric receptor therapies 普雷西根公司 2024-06-07 CN disclosed
EP-4274898-A2 CHIMERIC RECEPTOR THERAPY Precigen, Inc. (US) 2023-11-15 EP disclosed
EP-4251278-A1 HUMAN PAPILLOMA VIRUS VACCINES AND USES OF THE SAME FOR HPV ASSOCIATED DISEASES Precigen, Inc. (US) 2023-10-04 EP disclosed
WO-2022150732-A2 CHIMERIC RECEPTOR THERAPY PRECIGEN, INC. (US) 2022-07-14 WO disclosed
WO-2022115470-A1 HUMAN PAPILLOMA VIRUS VACCINES AND USES OF THE SAME FOR HPV ASSOCIATED DISEASES PRECIGEN, INC. (US) 2022-06-02 WO disclosed