⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28304448 | 0.78 | — | — | |
| SCHEMBL14427328 | 0.73 | — | — | |
| SCHEMBL5902457 | 0.73 | — | — | |
| SCHEMBL11358455 | 0.69 | — | — | |
| SCHEMBL9637535 | 0.67 | — | — | |
| SCHEMBL11102223 | 0.67 | — | — | |
| SCHEMBL25455313 | 0.67 | — | — | |
| SCHEMBL8650075 | 0.67 | — | — | |
| SCHEMBL3731819 | 0.65 | THRB (0.36) | — | |
| SCHEMBL14064876 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8722753-B2 | Hydroxyl terminated precursor and method of making the same | LEAR CORPORATION (US) | 2014-05-13 | — | — | US | disclosed |
| US-20100160593-A1 | ISOCYANATO TERMINATED PRECURSOR AND METHOD OF MAKING THE SAME | LEAR CORPORATION (US) | 2010-06-24 | — | — | US | disclosed |
| US-7678936-B2 | Isocyanato terminated precursor and method of making the same | LEAR CORPORATION (US) | 2010-03-16 | — | — | US | disclosed |
| WO-2009026426-A1 | ISOCYANATO TERMINATED PRECURSOR AND METHOD OF MAKING THE SAME | RENOSOL SYSTEMS, LLC (US) | 2009-02-26 | — | — | WO | disclosed |
| US-20090054611-A1 | HYDROXYL TERMINATED PRECURSOR AND METHOD OF MAKING THE SAME | LEAR CORPORATION | 2009-02-26 | — | — | US | disclosed |
| US-20090054604-A1 | ISOCYANATO TERMINATED PRECURSOR AND METHOD OF MAKING THE SAME | LEAR CORPORATION | 2009-02-26 | — | — | US | disclosed |
| WO-2009026424-A1 | HYDROXYL TERMINATED PRECURSOR AND METHOD OF MAKING THE SAME | RENOSOL SYSTEMS, LLC (US) | 2009-02-26 | — | — | WO | disclosed |