Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.37 |
| ▸ | MTOR | P42345 | 2/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.37 |
| ▸ | FEN1 | P39748 | 3/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
| ▸ | GABRD | O14764 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18201924 | 1.00 | NAMPT (0.41) | NAMPTPIK3CAMTORGPR119ALOX5AP | |
| SCHEMBL18201818 | 0.86 | KCNK3 (0.45) | NAMPTPIK3CAMTORGPR119ALOX5AP | |
| SCHEMBL16891558 | 0.84 | NAMPT (0.39) | NAMPTGPR119HDAC3HDAC4HDAC1 | |
| SCHEMBL16892090 | 0.84 | NAMPT (0.39) | NAMPTGPR119HDAC3HDAC4HDAC1 | |
| SCHEMBL18201933 | 0.83 | GPR119 (0.38) | NAMPTPIK3CAMTORGPR119ALOX5AP | |
| SCHEMBL18201815 | 0.83 | GPR119 (0.48) | GPR119ALOX5APFEN1HDAC1GABRP | |
| SCHEMBL18201922 | 0.83 | GPR119 (0.44) | GPR119HDAC1GABRPGABRDGABRA1 | |
| SCHEMBL1997213 | 0.78 | MEN1 (0.49) | GPR119MAP4K4 | |
| SCHEMBL30584532 | 0.78 | MEN1 (0.49) | GPR119MAP4K4 | |
| SCHEMBL18291485 | 0.77 | GPR119 (0.48) | GPR119HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3288931-B2 | CERTAIN PROTEIN KINASE INHIBITOR | CHONGQING FOCHON PHARMACEUTICAL CO LTD (CN) | 2022-07-20 | — | — | EP | disclosed |